ID   W8RZ47_9RHOB            Unreviewed;      1223 AA.
AC   W8RZ47;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN   ORFNames=roselon_00722 {ECO:0000313|EMBL:AHM03147.1};
OS   Roseibacterium elongatum DSM 19469.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Roseibacterium.
OX   NCBI_TaxID=1294273 {ECO:0000313|EMBL:AHM03147.1, ECO:0000313|Proteomes:UP000019593};
RN   [1] {ECO:0000313|EMBL:AHM03147.1, ECO:0000313|Proteomes:UP000019593}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19469 {ECO:0000313|Proteomes:UP000019593};
RA   Fiebig A., Goeker M., Klenk H.-P.P.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP004372; AHM03147.1; -; Genomic_DNA.
DR   AlphaFoldDB; W8RZ47; -.
DR   STRING; 1294273.roselon_00722; -.
DR   KEGG; red:roselon_00722; -.
DR   PATRIC; fig|1294273.3.peg.711; -.
DR   eggNOG; COG2304; Bacteria.
DR   HOGENOM; CLU_268423_0_0_5; -.
DR   OrthoDB; 9783818at2; -.
DR   Proteomes; UP000019593; Chromosome.
DR   CDD; cd00198; vWFA; 1.
DR   Gene3D; 2.60.120.380; -; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 1.10.101.10; PGBD-like superfamily/PGBD; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR   InterPro; IPR036365; PGBD-like_sf.
DR   InterPro; IPR036366; PGBDSf.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR   PANTHER; PTHR10579:SF43; LOW QUALITY PROTEIN: EPITHELIAL CHLORIDE CHANNEL PROTEIN-LIKE ISOFORM X1-RELATED; 1.
DR   Pfam; PF13519; VWA_2; 1.
DR   Pfam; PF13768; VWA_3; 1.
DR   SMART; SM00327; VWA; 2.
DR   SUPFAM; SSF47090; PGBD-like; 1.
DR   SUPFAM; SSF53300; vWA-like; 2.
DR   PROSITE; PS50234; VWFA; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000019593};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..1223
FT                   /note="VWFA domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004912808"
FT   DOMAIN          614..788
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   DOMAIN          827..1022
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          139..171
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          495..520
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        143..158
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1223 AA;  129494 MW;  BE30DF1D65890CF2 CRC64;
     MRAWRRIVFV SALLAGGGFA AVVGAQPVEL AQTAYEPMTE ARTVTAGWQA VRAELTIRNS
     GAAPLDLSGL PGRIEILEDG VFPYLPEVVT WNGAASPESL LLPAGMAGTL ALEFELPQTH
     GALVLRVTTA LGAVEAPLGA DVPAPTVDPP PARQTDPALP APQDPTRTDG PQFACLTGPE
     AEAATTGALV SLARQGASIA LERGRAVQNL GYLLDERLDS YDFFVNAERD AEGVVAFVVS
     LAGTRAATVS HIALDSRTRS TLNWVPATVR IELSDIGAEG PWTDLGMLTM EDRPEALELF
     ALATPAPARA VRITIGTSWR PGVRLSEIQI FESAAAPSVL SDVATDLAAV DNGGRIARFT
     SQAGSRDAAN ILSATGSWMP ATNRFPQDIT VAFDDFRTMR VTDIALDWQI GPEADWAPRV
     RVAASTAPGP LTGMQDLGLM TAERTGPDRG RTGLRFDETV PIRWLTLTIS DPGSATFQLD
     RLRVTGTAAD LFSSREGSSI AADGGSGSGL PGEVEPNDGL ADATPLPMGA VIEGGAGSLG
     DLDHFAFSVP AGPDRTVNFR LEGRPWIRAR LDLIGPDGDV LFGQDPLTAE TARTFTWRLP
     SGTYHVRLSQ PAPSIALVID DSGSMGDAIF TAIEAARLFV TSKAPEEQIS LTSFSGIIRP
     LLPLTTDAAA LDRAMREGID QSHPQGTSVY DAVRAGIETL EDAGGNRAII LLTDGEDVSG
     APYPAFWDTI ETERIPIYAI GLGDAMRSYT PNVSARLDHM LEAIARGSGG AYFDSPAAED
     LPRVWQDIAA AIRAPADYAV SWSTGDDGAL AVLENGEEFV SADALGELLF ILDASGSMRA
     ATDQGRRRID VARSLMFDIL SEIPDSTPLG LRIYGANLPD QPATASCRDS VLAVPVAPGS
     VDRAIDAVLA ASPRGQTPIG RSLAMVPQDL GPGDRGLVIL ITDGEETCDA EVDAPFNPER
     VANDLMARGI DIRVNIVGFD IGDPEVQAGL ARVAEVTGGA FYPAEGQAGL QAALRAALVP
     EIEVRDDLGQ VIAETRVGAP AIALPEGHYQ LLLGGDEHLI ARQSIPARQE RRVYVNREGE
     EVRITSEVVA PGTALPEAVR IDVAQAVAAE DRPVLDRLLV RSRTPRRPIL MEERVHGIQA
     RLIDLGFDPG PADGQMGART RAAADAFLAR YGMVLPNRPA FDAGGEPTHD LWFSLVATHT
     ERLLVPLHRG LPDTPELARL RAQ
//