ID W8TKF1_PEPAC Unreviewed; 756 AA.
AC W8TKF1;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Diguanylate cyclase YdaM {ECO:0000313|EMBL:AHM58208.1};
DE EC=2.7.7.65 {ECO:0000313|EMBL:AHM58208.1};
GN Name=ydaM1 {ECO:0000313|EMBL:AHM58208.1};
GN ORFNames=EAL2_808p07050 {ECO:0000313|EMBL:AHM58208.1};
OS Peptoclostridium acidaminophilum DSM 3953.
OG Plasmid EAL2_808p {ECO:0000313|EMBL:AHM58208.1,
OG ECO:0000313|Proteomes:UP000019591}.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC Peptoclostridium.
OX NCBI_TaxID=1286171 {ECO:0000313|EMBL:AHM58208.1, ECO:0000313|Proteomes:UP000019591};
RN [1] {ECO:0000313|EMBL:AHM58208.1, ECO:0000313|Proteomes:UP000019591}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 3953 {ECO:0000313|EMBL:AHM58208.1,
RC ECO:0000313|Proteomes:UP000019591};
RC PLASMID=Plasmid EAL2_808p {ECO:0000313|Proteomes:UP000019591};
RX PubMed=24926057;
RA Poehlein A., Andreesen J.R., Daniel R.;
RT "Complete Genome Sequence of Amino Acid-Utilizing Eubacterium
RT acidaminophilum al-2 (DSM 3953).";
RL Genome Announc. 2:e00573-14(2014).
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DR EMBL; CP007453; AHM58208.1; -; Genomic_DNA.
DR RefSeq; WP_025437041.1; NZ_CP007453.1.
DR AlphaFoldDB; W8TKF1; -.
DR KEGG; eac:EAL2_808p07050; -.
DR PATRIC; fig|1286171.3.peg.2887; -.
DR eggNOG; COG2199; Bacteria.
DR eggNOG; COG5001; Bacteria.
DR eggNOG; COG5002; Bacteria.
DR HOGENOM; CLU_368326_0_0_9; -.
DR OrthoDB; 9805474at2; -.
DR Proteomes; UP000019591; Plasmid EAL2_808p.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0052621; F:diguanylate cyclase activity; IEA:UniProtKB-EC.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 2.
DR CDD; cd12913; PDC1_MCP_like; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08447; PAS_3; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotidyltransferase {ECO:0000313|EMBL:AHM58208.1};
KW Plasmid {ECO:0000313|EMBL:AHM58208.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019591};
KW Transferase {ECO:0000313|EMBL:AHM58208.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 297..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 344..417
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 422..474
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 468..538
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 620..749
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 756 AA; 85916 MW; 1439A2A88414CBB5 CRC64;
MLSVVVVSIS YYSKYNSLID EFENTAMSKE FLLREHIRMS SNFIKSMMIH GNTFFEHGSS
SDSEFYGLLK YDPKSDSFSM DAAEGTPQEK AVGNITGLGE IPESGKVRDE LNLALQYNKF
FGSHYEKFPE VAWLYYTSEN NFVNMYPWIS SKDFTFLEKL KTVEFYKIAN PLHNPFRRIV
WSPAYIDEAG KGTMITLSAP IYDKDNFKGV VSLDLTTAWL AKIIASDYEG YLIEDTNSIL
SVSHSRISNV SDSELDALMK IPAKDFEKLK KLKLNEVQIL DGYYIYLASF SEAPWKLFYI
VPMWLVAGKA AASALPILLI SVFLIISMNQ IEKRKKSEEL LKREKELLET TFFSIAEGII
VADKAGRITL MNAVAEKYTG WTKEEALGRD FHEVYNNINI ETRERRYNPV AHVLETGKNI
RSDRYISLIS RDGSESYILG SAAGIISDAG ELSGVVVSFR DITKEYEQER EIAEFLNINL
DMLCVVDTDG KFHKVNKRFE EILGYNTEEL EGRSILSLVH KDDTMFMLNV YRELLENKTV
SAFTARCRCK DGSERYIEWH AQIGSGKYIY SSARDVTEKR VLEERLRMSA TKDELTSLYN
RHFFESIIAQ QTGMADITGE AISIALIDLD QFKQVNDTWG HPAGDELLKS TAQTIERTLR
KSDILARFGG EEFIVLMPKT SIEGAVAASE KIRSAIEIHM HPTMGKQTAS IGVAERAESE
AFSSWYARVD EALYRAKHGG RNCVVVAREP DREYHS
//
