ID W8VZH0_9FLAO Unreviewed; 742 AA.
AC W8VZH0;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=PNPLA domain-containing protein {ECO:0000259|PROSITE:PS51635};
GN ORFNames=NMS_0552 {ECO:0000313|EMBL:BAO54561.1};
OS Nonlabens marinus S1-08.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Nonlabens.
OX NCBI_TaxID=1454201 {ECO:0000313|EMBL:BAO54561.1, ECO:0000313|Proteomes:UP000031760};
RN [1] {ECO:0000313|EMBL:BAO54561.1, ECO:0000313|Proteomes:UP000031760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S1-08 {ECO:0000313|EMBL:BAO54561.1,
RC ECO:0000313|Proteomes:UP000031760};
RX PubMed=24706784; DOI=10.1073/pnas.1403051111;
RA Yoshizawa S., Kumagai Y., Kim H., Ogura Y., Hayashi T., Iwasaki W.,
RA DeLong E.F., Kogure K.;
RT "Functional characterization of flavobacteria rhodopsins reveals a unique
RT class of light-driven chloride pump in bacteria.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:6732-6737(2014).
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DR EMBL; AP014548; BAO54561.1; -; Genomic_DNA.
DR RefSeq; WP_041495275.1; NZ_AP014548.1.
DR AlphaFoldDB; W8VZH0; -.
DR STRING; 1454201.NMS_0552; -.
DR HOGENOM; CLU_014750_2_0_10; -.
DR OrthoDB; 9770965at2; -.
DR Proteomes; UP000031760; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd07205; Pat_PNPLA6_PNPLA7_NTE1_like; 1.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 2.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR043864; Omp85-like_dom.
DR InterPro; IPR002641; PNPLA_dom.
DR PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR PANTHER; PTHR14226:SF82; PATATIN-LIKE PROTEIN, PLPD; 1.
DR Pfam; PF19143; Omp85_2; 1.
DR Pfam; PF01734; Patatin; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS51635; PNPLA; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098}.
FT DOMAIN 33..223
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
SQ SEQUENCE 742 AA; 83179 MW; B97EE5E4F8484308 CRC64;
MITLVLMGQF CLSQTTPVKD SLLHYDGSQK IGLVLSGGGA KGLAHIGTLK VIDSLGIKID
YIAGTSMGAI VGSLYASGYT GQQIDSIFKV TNFNNIISDE IPRSAKTFYE RRENERYAVT
LPFEDFKIKL PNSLSKGQNV YNLLSQVLSH VNDVNDFTKL PIPFFCLATD IETGQEVVLD
SGYLPRAVNA SGALPSLFAP VQIDNRMLID GGVTDNYPIE KLRAKGMDII IGVDVQDDFK
SLDELTDAFS ILTQINNFRT INDMKLKAPK TDIYIQPNIK NFTVISFDQG TAIVEKGRVA
ALAQIGLLNQ LSNAAYQKPK LKTVSNDRLY LSNININGNE RYTRSYVIGK FKLTTPGFTT
YENIKNGVNN LQATNNFTKI NYELIPHEEG LELDVTVEES TVRNYLRLSL HYDELLRSAA
LVNLTRKNVL FNNDVVSADF ILGDNLRYVA DYYIDKGNYW SIGLHSEFTQ FEKDIPTSFI
NSVTGTLPVG VNSVEINYYD WTQQFYLQTR LDKGFNVIAG AELKSLDIFT NTLVTGSVTD
NRTDFENSTT GSIYGKALYD TYDNNFFPSS GWKVDADFHL YLYNDVLQED FSEYSIAQLQ
VGYARAFGKF SLRAEGHVGI SIGNPETSSL DFVLGGYGAR RINNLIPFYG YDFISLSGNT
MMRSLFELDY EIFRKNHVVL SANFANLDDD LFEQDDWYSK ARYSGFAVGY GVETFLGPLE
LKYSFSPQQD DGEFFVRLGF NF
//
