ID W8W0H2_9FLAO Unreviewed; 351 AA.
AC W8W0H2;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Naringenin-chalcone synthase {ECO:0000313|EMBL:BAO56321.1};
GN ORFNames=NMS_2312 {ECO:0000313|EMBL:BAO56321.1};
OS Nonlabens marinus S1-08.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Nonlabens.
OX NCBI_TaxID=1454201 {ECO:0000313|EMBL:BAO56321.1, ECO:0000313|Proteomes:UP000031760};
RN [1] {ECO:0000313|EMBL:BAO56321.1, ECO:0000313|Proteomes:UP000031760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S1-08 {ECO:0000313|EMBL:BAO56321.1,
RC ECO:0000313|Proteomes:UP000031760};
RX PubMed=24706784; DOI=10.1073/pnas.1403051111;
RA Yoshizawa S., Kumagai Y., Kim H., Ogura Y., Hayashi T., Iwasaki W.,
RA DeLong E.F., Kogure K.;
RT "Functional characterization of flavobacteria rhodopsins reveals a unique
RT class of light-driven chloride pump in bacteria.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:6732-6737(2014).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531}.
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DR EMBL; AP014548; BAO56321.1; -; Genomic_DNA.
DR RefSeq; WP_041496807.1; NZ_AP014548.1.
DR AlphaFoldDB; W8W0H2; -.
DR STRING; 1454201.NMS_2312; -.
DR HOGENOM; CLU_034992_0_1_10; -.
DR OrthoDB; 9786288at2; -.
DR Proteomes; UP000031760; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
FT DOMAIN 25..201
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 219..349
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 141
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 351 AA; 38987 MW; 91686B8E5AED4B3F CRC64;
MSVTIKSVAT VTPQYSKQTS EILPFVETWL ADQDERLRRK TIKIFEGAAV DKRYSIMDPV
EVFTKTSFQD RNDIYRREVV PLAKTAVEQA LSKANWVPQD LDYIITVSCT GIMIPSIDAY
LINEMNMRQD IVRLPVTEMG CVAGISGLIY ADNFLRANPG KKAAVVAIEA PTATFQINDY
SMANMVSAAI FGDGCACVLL SSVEGGEGPQ IKGHEMYHFP DATHMMGFDL VDSGLKMVLD
KEVPETIAAH FPAIIHPFLK KHELEIKDID HLIFHPGGKK IVQTVEALFS DLGKNIDDTK
EVLRLYGNMS SATVLFVLDR FMNKSNVKKG DTGLMLSFGP GFTAQRILVQ W
//
