ID W9ADS0_9BACI Unreviewed; 399 AA.
AC W9ADS0;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Starvation-sensing protein RspA {ECO:0000313|EMBL:CDO03608.1};
GN Name=rspA {ECO:0000313|EMBL:CDO03608.1};
GN ORFNames=BN988_02125 {ECO:0000313|EMBL:CDO03608.1};
OS Oceanobacillus picturae.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Oceanobacillus.
OX NCBI_TaxID=171693 {ECO:0000313|EMBL:CDO03608.1, ECO:0000313|Proteomes:UP000028863};
RN [1] {ECO:0000313|EMBL:CDO03608.1, ECO:0000313|Proteomes:UP000028863}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S1 {ECO:0000313|EMBL:CDO03608.1,
RC ECO:0000313|Proteomes:UP000028863};
RA Croce O., Lagier J.C., Raoult D.;
RT "Draft genome sequencing of Oceanobacillus picturae strain S1 isolated from
RT human gut.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDO03608.1, ECO:0000313|Proteomes:UP000028863}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S1 {ECO:0000313|EMBL:CDO03608.1,
RC ECO:0000313|Proteomes:UP000028863};
RA Urmite Genomes U.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Has no detectable activity with D-mannonate and with a panel
CC of 70 other acid sugars (in vitro), in spite of the conservation of the
CC residues that are expected to be important for catalytic activity and
CC cofactor binding. May have evolved a divergent function.
CC {ECO:0000256|ARBA:ARBA00003553}.
CC -!- SIMILARITY: Belongs to the mandelate racemase/muconate lactonizing
CC enzyme family. GalD subfamily. {ECO:0000256|ARBA:ARBA00010339}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDO03608.1}.
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DR EMBL; CCAX010000001; CDO03608.1; -; Genomic_DNA.
DR RefSeq; WP_036575821.1; NZ_CCAX010000001.1.
DR AlphaFoldDB; W9ADS0; -.
DR STRING; 171693.BN988_02125; -.
DR eggNOG; COG4948; Bacteria.
DR Proteomes; UP000028863; Unassembled WGS sequence.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR GO; GO:0009063; P:amino acid catabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR InterPro; IPR034589; D-mannonate_dehydratase-like.
DR InterPro; IPR034593; DgoD-like.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR029065; Enolase_C-like.
DR InterPro; IPR018110; Mandel_Rmase/mucon_lact_enz_CS.
DR InterPro; IPR013342; Mandelate_racemase_C.
DR InterPro; IPR013341; Mandelate_racemase_N_dom.
DR PANTHER; PTHR48080; D-GALACTONATE DEHYDRATASE-RELATED; 1.
DR PANTHER; PTHR48080:SF6; STARVATION-SENSING PROTEIN RSPA; 1.
DR Pfam; PF13378; MR_MLE_C; 1.
DR Pfam; PF02746; MR_MLE_N; 1.
DR SFLD; SFLDS00001; Enolase; 1.
DR SFLD; SFLDG00033; mannonate_dehydratase; 1.
DR SMART; SM00922; MR_MLE; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
DR PROSITE; PS00908; MR_MLE_1; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000028863}.
FT DOMAIN 132..252
FT /note="Mandelate racemase/muconate lactonizing enzyme C-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00922"
SQ SEQUENCE 399 AA; 45489 MW; 147B19CFCFEF5C4D CRC64;
MSPILITDVK CYITRPDRHN LIVVKVETNK GVHGYGCATF QQRPLAVKTM VDEYLKPILI
GKDANNIEDI WQMMMVNSYW RNGPVINNAV SGVDMALWDI KGKQANMPLY QLFGGKSRDA
IASYTHAVAD NLDELYKQID TILEEGYQHI RCQLGFYGGL ADQLLTTENP SIGSYFDQNS
YMQTTVHMFK SIREKYGFSF EILHDVHERL FPNQAINFAK DVEAYKPYYI EDILPPDQNE
WLEQLRSQSA TPLATGELFN NPMEWKELIT NRRVDYMRCH VSQIGGITPA LKLAHFCDAM
GIRMAWHTPS DITPIGMAVN THLNIHLHNA AIQENIHVKE TTASLFSYVP KPKKGFLYPI
DKPGIGVDFD EEKAAEYPVV YRAHEWTQSR IPDGTIVTP
//
