ID   W9AKN6_9BACI            Unreviewed;       592 AA.
AC   W9AKN6;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Beta-glucuronidase {ECO:0000313|EMBL:CDO03467.1};
GN   Name=uidA {ECO:0000313|EMBL:CDO03467.1};
GN   ORFNames=BN988_01983 {ECO:0000313|EMBL:CDO03467.1};
OS   Oceanobacillus picturae.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Oceanobacillus.
OX   NCBI_TaxID=171693 {ECO:0000313|EMBL:CDO03467.1, ECO:0000313|Proteomes:UP000028863};
RN   [1] {ECO:0000313|EMBL:CDO03467.1, ECO:0000313|Proteomes:UP000028863}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S1 {ECO:0000313|EMBL:CDO03467.1,
RC   ECO:0000313|Proteomes:UP000028863};
RA   Croce O., Lagier J.C., Raoult D.;
RT   "Draft genome sequencing of Oceanobacillus picturae strain S1 isolated from
RT   human gut.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CDO03467.1, ECO:0000313|Proteomes:UP000028863}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S1 {ECO:0000313|EMBL:CDO03467.1,
RC   ECO:0000313|Proteomes:UP000028863};
RA   Urmite Genomes U.;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC       {ECO:0000256|ARBA:ARBA00007401}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDO03467.1}.
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DR   EMBL; CCAX010000001; CDO03467.1; -; Genomic_DNA.
DR   AlphaFoldDB; W9AKN6; -.
DR   STRING; 171693.BN988_01983; -.
DR   eggNOG; COG3250; Bacteria.
DR   Proteomes; UP000028863; Unassembled WGS sequence.
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR006103; Glyco_hydro_2_cat.
DR   InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR   InterPro; IPR006104; Glyco_hydro_2_N.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR   PANTHER; PTHR42732:SF3; BETA-MANNOSIDASE; 1.
DR   Pfam; PF00703; Glyco_hydro_2; 1.
DR   Pfam; PF02836; Glyco_hydro_2_C; 1.
DR   Pfam; PF02837; Glyco_hydro_2_N; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028863}.
FT   DOMAIN          29..184
FT                   /note="Glycosyl hydrolases family 2 sugar binding"
FT                   /evidence="ECO:0000259|Pfam:PF02837"
FT   DOMAIN          192..294
FT                   /note="Glycoside hydrolase family 2 immunoglobulin-like
FT                   beta-sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF00703"
FT   DOMAIN          329..588
FT                   /note="Glycoside hydrolase family 2 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF02836"
SQ   SEQUENCE   592 AA;  69124 MW;  B52C18CD51BF7423 CRC64;
     MKEATMKAGK TYQRTEYPRP QFQRDAWMNL NGKWKFAFDD ENKGEQGRWF DQYTYPSEII
     VPFTYETKAS GIGEEAFHPY VWYSRTFLIP EEEIGKRTVL RFQASDYITK VWVNGSYIGQ
     HTGGNAAFSF DITKAVDSAS ENELTVKVED SQSCVQPRGK QRWINENFGC WYVQNTGIWQ
     TVWLEFLEEN SLDHVKITPK VDSNSVVFDY TLHGELPRNS RLETVISFNG KQVKQFTTVL
     DRSTFHLEVD LAADIHEWKV LHWSPEHPNL YDVKFRLYVD DVLKDEVDSY FGMRKISIKD
     GKVLLNNVPI YQKLLLDQGY WPDTMLTPPS DEAILEDIDK TLAMGYNGVR KHQKIEDDRF
     LYWCDKKGLL VWSEMAATYE FSDQAVENFT KEWLDIVQQH YNHPSIITWV PFNESWGVPH
     IFKDKQQQAF TESIYYLTKS LDAERPVIVN DGWEHTVSDI IALHDYEESG KTLYERYKDM
     DAILQNKIPH NNHRYAFAEG YQYKGQPIML TEYGGIAFKD ESGWGYGNQV STEEEFLKRY
     KETTDAIKAI PEISGYCYTQ TTDVQQEING LLKENREPKI AMEKIKQVND AT
//