ID W9C575_SCLBF Unreviewed; 374 AA.
AC W9C575;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Methyltransferase LaeA {ECO:0008006|Google:ProtNLM};
GN ORFNames=SBOR_8573 {ECO:0000313|EMBL:ESZ91031.1};
OS Sclerotinia borealis (strain F-4128).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Sclerotiniaceae; Sclerotinia.
OX NCBI_TaxID=1432307 {ECO:0000313|EMBL:ESZ91031.1, ECO:0000313|Proteomes:UP000019487};
RN [1] {ECO:0000313|EMBL:ESZ91031.1, ECO:0000313|Proteomes:UP000019487}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F-4157 {ECO:0000313|Proteomes:UP000019487};
RX PubMed=24459262; DOI=10.1128/genomeA.01175-13;
RA Mardanov A.V., Beletsky A.V., Kadnikov V.V., Ignatov A.N., Ravin N.V.;
RT "Draft genome sequence of Sclerotinia borealis, a psychrophilic plant
RT pathogenic fungus.";
RL Genome Announc. 2:E0117513-E0117513(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-methionyl-[protein] + S-adenosyl-L-methionine = S-adenosyl-
CC L-homocysteine + S-methyl-L-methionyl-[protein];
CC Xref=Rhea:RHEA:60560, Rhea:RHEA-COMP:12313, Rhea:RHEA-COMP:15592,
CC ChEBI:CHEBI:16044, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:142742; Evidence={ECO:0000256|ARBA:ARBA00036003};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:60561;
CC Evidence={ECO:0000256|ARBA:ARBA00036003};
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. LaeA
CC methyltransferase family. {ECO:0000256|ARBA:ARBA00038158}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESZ91031.1}.
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DR EMBL; AYSA01000550; ESZ91031.1; -; Genomic_DNA.
DR AlphaFoldDB; W9C575; -.
DR STRING; 1432307.W9C575; -.
DR HOGENOM; CLU_010595_2_0_1; -.
DR OrthoDB; 2241530at2759; -.
DR Proteomes; UP000019487; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43591; METHYLTRANSFERASE; 1.
DR PANTHER; PTHR43591:SF30; PROTEIN-METHIONINE METHYLTRANSFERASE LAEA; 1.
DR Pfam; PF13489; Methyltransf_23; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000019487}.
SQ SEQUENCE 374 AA; 43205 MW; E84D8CE9E171B6C9 CRC64;
MLPKEIDINN CSVANANSIH ATKLAEQAKP VRDDRSRGRF ASMVVAMAMS NNNGTSSPAP
SAGPQELPKD YYEHYRLYHG FHKGKYMFPC DEQEMDRYDI FHKFFQVAMG GVLHSKNTKF
TNNFDGPRIL DLGTGTGIWA IDMAEKYGTP NGQGEVLGLD LAKIQPLFIP SNLTFWQRDI
ESPWYGLEIE SWDMIHIRML SGGIVSWKDI YQKAFRHLKP VYGRLEHVEM DFTPRTDFGE
IPADSTLVTW IGKLFDATHR NYRPLAYNTE TREMLTREGF VDIEEEVIKI PLNPWPDDLR
EKDVARWYNL ALTQGLEAMT LAPMYRIYGW TPDDVTRLTT EVRREICSRK IRAYNNMHIW
TARRPEKADE TIPL
//
