ID W9C7R4_SCLBF Unreviewed; 448 AA.
AC W9C7R4;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Saccharopine dehydrogenase {ECO:0000313|EMBL:ESZ90630.1};
GN ORFNames=SBOR_8988 {ECO:0000313|EMBL:ESZ90630.1};
OS Sclerotinia borealis (strain F-4128).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Sclerotiniaceae; Sclerotinia.
OX NCBI_TaxID=1432307 {ECO:0000313|EMBL:ESZ90630.1, ECO:0000313|Proteomes:UP000019487};
RN [1] {ECO:0000313|EMBL:ESZ90630.1, ECO:0000313|Proteomes:UP000019487}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F-4157 {ECO:0000313|Proteomes:UP000019487};
RX PubMed=24459262; DOI=10.1128/genomeA.01175-13;
RA Mardanov A.V., Beletsky A.V., Kadnikov V.V., Ignatov A.N., Ravin N.V.;
RT "Draft genome sequence of Sclerotinia borealis, a psychrophilic plant
RT pathogenic fungus.";
RL Genome Announc. 2:E0117513-E0117513(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESZ90630.1}.
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DR EMBL; AYSA01000594; ESZ90630.1; -; Genomic_DNA.
DR AlphaFoldDB; W9C7R4; -.
DR STRING; 1432307.W9C7R4; -.
DR HOGENOM; CLU_016207_3_1_1; -.
DR OrthoDB; 2184985at2759; -.
DR Proteomes; UP000019487; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1870.10; Domain 3, Saccharopine reductase; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032095; Sacchrp_dh-like_C.
DR InterPro; IPR005097; Sacchrp_dh_NADP.
DR PANTHER; PTHR11133:SF25; ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11133; SACCHAROPINE DEHYDROGENASE; 1.
DR Pfam; PF16653; Sacchrp_dh_C; 1.
DR Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW Lysine biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000019487}.
FT DOMAIN 9..123
FT /note="Saccharopine dehydrogenase NADP binding"
FT /evidence="ECO:0000259|Pfam:PF03435"
FT DOMAIN 127..440
FT /note="Saccharopine dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16653"
SQ SEQUENCE 448 AA; 49262 MW; BF6B7BAD554EB8AC CRC64;
MAGFASKKVL MLGAGFVTRP TLDILSEAGI QVSVACRTLE SAKKLSEGVK NAHPISLDVT
DDKALDAEVA KNDLVISLIP YTFHATVIKS AIRNKKNVVT TSYVSPAMME LDEDAKNAGI
TVMNEIGLDP GIDHLYAVKT IEEVHKAGGK ILSFLSYCGG LPAPEASDNP LGYKFSWSSR
GVLLALRNAA RFYRDGKVVD VAGPELMGTA KPYFIYPGYA FVAYPNRDST PYKERYNIPE
AQTIIRGTLR YQGFPEFIRV LVDMGFLSDE DQGFSKPISW KEATQKVLAA SSSSEEDLKW
AIASKAKFES TEEKERIMNG LSWVGIFSDE KIIPRGNPLD TLCATLEKKM QFEEGERDFV
LLQHKFEIEH KDGKKETRTS TLVEYGDPKG YSAMAKLVGV PCGVAVKQVL DGTISEKGIL
APMTSKINDP LMEELKKYGI TLVEKTIS
//
