ID W9DR23_METTI Unreviewed; 629 AA.
AC W9DR23;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN ORFNames=MettiDRAFT_1366 {ECO:0000313|EMBL:ETA67925.1};
OS Methanolobus tindarius DSM 2278.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanolobus.
OX NCBI_TaxID=1090322 {ECO:0000313|EMBL:ETA67925.1, ECO:0000313|Proteomes:UP000019483};
RN [1] {ECO:0000313|EMBL:ETA67925.1, ECO:0000313|Proteomes:UP000019483}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2278 {ECO:0000313|EMBL:ETA67925.1,
RC ECO:0000313|Proteomes:UP000019483};
RG DOE Joint Genome Institute;
RA Eisen J., Huntemann M., Han J., Chen A., Kyrpides N., Mavromatis K.,
RA Markowitz V., Palaniappan K., Ivanova N., Schaumberg A., Pati A.,
RA Liolios K., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETA67925.1}.
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DR EMBL; AZAJ01000001; ETA67925.1; -; Genomic_DNA.
DR RefSeq; WP_023845061.1; NZ_AZAJ01000001.1.
DR AlphaFoldDB; W9DR23; -.
DR STRING; 1090322.MettiDRAFT_1366; -.
DR OrthoDB; 371752at2157; -.
DR Proteomes; UP000019483; Unassembled WGS sequence.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ETA67925.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 29..82
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 88..473
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 528..606
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 629 AA; 70919 MW; 2DEE0A5095BD8E6F CRC64;
MSENFDVKLD GKSYLPDPSV KENSWIGDYE TAYNEFLKDP EKHWENVAEE LEWFEKWDKV
REWDHPYAKW FTNAKMNITH NCLDRHVMNG KRNKVAIIWV GDDGKEEILT YRQLYREVMR
FANGLKSLGV EKGDRVCIYM PFVPEQIIAM LACARIGAVH SVVFGGFGAN ALHSRIKDAQ
AKIVITADAS LRRGKRIDLK TLVDEAVVNA SSVEKIVVLR RMTPQMELFS EIEVDFYEIM
EDVEKECEPE VMDSEDPLFI LYTSGTTGPA KGIVHACGGY MVGTYYTTKN MFDLQESDVM
WCTADPGWIT GHSYIVYGPL AMGATILISE TTPDYPDPGV WWSMIEEFDV TIFYTAPTAI
RMFMRMGEEW PEKYNLSSLR ILGSVGEPLN PEAFEWYYRV IGKEKCPILD TWWQTETGMH
MLTTAIGEPM KPGFAGRPVP GIVADVVDEN GEPVPAGTGG FLVIKEPWPS MMRTVYNNDE
RYRQYWSTVG NYYAAGDLAV KDEDGYIMIL GRSDDVLIVA GHNIGSAEVE SALVSHEAVA
EAAVIGKPDP LKGDSIKAFI ILRMGYTASD KLKLELVYHV RMNLGPIAIP SEIEFVESLP
KTRSGKIMRR LLKAQELGQD PGDISTLED
//
