ID W9DT44_METTI Unreviewed; 696 AA.
AC W9DT44;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=MettiDRAFT_2462 {ECO:0000313|EMBL:ETA68973.1};
OS Methanolobus tindarius DSM 2278.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanolobus.
OX NCBI_TaxID=1090322 {ECO:0000313|EMBL:ETA68973.1, ECO:0000313|Proteomes:UP000019483};
RN [1] {ECO:0000313|EMBL:ETA68973.1, ECO:0000313|Proteomes:UP000019483}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2278 {ECO:0000313|EMBL:ETA68973.1,
RC ECO:0000313|Proteomes:UP000019483};
RG DOE Joint Genome Institute;
RA Eisen J., Huntemann M., Han J., Chen A., Kyrpides N., Mavromatis K.,
RA Markowitz V., Palaniappan K., Ivanova N., Schaumberg A., Pati A.,
RA Liolios K., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000256|ARBA:ARBA00008010,
CC ECO:0000256|RuleBase:RU004070}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETA68973.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AZAJ01000001; ETA68973.1; -; Genomic_DNA.
DR RefSeq; WP_023846107.1; NZ_AZAJ01000001.1.
DR AlphaFoldDB; W9DT44; -.
DR STRING; 1090322.MettiDRAFT_2462; -.
DR OrthoDB; 6747at2157; -.
DR Proteomes; UP000019483; Unassembled WGS sequence.
DR GO; GO:0042555; C:MCM complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR Gene3D; 2.20.28.10; -; 1.
DR Gene3D; 3.30.1640.10; mini-chromosome maintenance (MCM) complex, chain A, domain 1; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR008047; MCM_4.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR027925; MCM_N.
DR InterPro; IPR033762; MCM_OB.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR PANTHER; PTHR11630:SF43; DNA REPLICATION LICENSING FACTOR MCM6; 1.
DR Pfam; PF00493; MCM; 1.
DR Pfam; PF17855; MCM_lid; 1.
DR Pfam; PF14551; MCM_N; 1.
DR Pfam; PF17207; MCM_OB; 1.
DR PRINTS; PR01657; MCMFAMILY.
DR PRINTS; PR01660; MCMPROTEIN4.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50051; MCM_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004070};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004070};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ETA68973.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004070}.
FT DOMAIN 273..480
FT /note="MCM"
FT /evidence="ECO:0000259|PROSITE:PS50051"
SQ SEQUENCE 696 AA; 78183 MW; 4CAA32DE139BFDE3 CRC64;
MTEGKWDEKF VVFLKKYYWD DILQLANSYP DQRSLEVDFY DLDVFDREIA NELLFNPDEV
MPSANNALQQ IDLPVEKKLI DAKVRFIKIP NKIPNRDLRS KHLLQFVAIE GMIRKATEVR
PKVLNAAFQC MRCEHVTMVP QNEIKFVEPV ECENETCGRK GPFKILVNQS VFVDAQKLQI
QESPENLKGG TQPQSLDVDI EDDLAGLVKP GDRVIINGVL RSHQRTTREG KSPFYDLVLH
ANSIEYTDLE FDELEITPEE EEEILALSRD PEIYQKVIGS IAPSIYGYEE VKEALSLQLF
SGVAKHLPDG SRVRGDIHML FMGDPGVAKS QLLRYMVKLS PRGVFASGKS ASSSGLTAAA
VRDDLGDGRW TLEAGALVMA DMGIAAVDEM DKMSTEDKSA LHEAMEQQTI SVAKAGILAT
LKSRCALLGA ANPKYGRFDR YEGIAQQINM PPALISRFDM IFVLLDTPNE DMDSKIAKHI
LKSHYAGELS EQRKNLPSST ITQEQVDGHM EVIKPVIDPD FLRKYVAYSR RNIFPVMEDD
ARDHLVKFYM DLRRMGDGKD APVPVTARQL EALVRLAEAS ARLRLSNVAN MDDAKRTTRI
VYSCLRQVGV DPDTGAFDVD VIASGTSKSQ RDRIKIVKEI IKSVGEKHPG GKAPLEEVYA
EAQNQQIDRQ HAEDLIARMR RSGDLIKPDK EHVKVV
//
