ID W9GPV8_9MICO Unreviewed; 686 AA.
AC W9GPV8;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=N864_00515 {ECO:0000313|EMBL:EWT05924.1};
OS Intrasporangium chromatireducens Q5-1.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Intrasporangium.
OX NCBI_TaxID=584657 {ECO:0000313|EMBL:EWT05924.1, ECO:0000313|Proteomes:UP000019494};
RN [1] {ECO:0000313|Proteomes:UP000019494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Q5-1 {ECO:0000313|Proteomes:UP000019494};
RA Liu H., Wang G.;
RT "Intrasporangium oryzae NRRL B-24470.";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWT05924.1}.
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DR EMBL; AWQS01000076; EWT05924.1; -; Genomic_DNA.
DR RefSeq; WP_051518451.1; NZ_AWQS01000076.1.
DR AlphaFoldDB; W9GPV8; -.
DR PATRIC; fig|584657.3.peg.2160; -.
DR OrthoDB; 9757990at2; -.
DR Proteomes; UP000019494; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EWT05924.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000019494};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 217..270
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 468..686
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 686 AA; 73551 MW; 4862594F8DF1EF3B CRC64;
MILGRRRRPG GSASAHVRTL VIVLVVLIPL GTLASLLMIS QQGRTVRTLT LSLGPAVEAN
TTVLLEMTRA RGTWLDSQWG AGLPATLAAL EAHRSSAEAE LEALDAATAR EELPSPHRSA
YTELTQRQRQ TIGAWFVAAE RSARAGPGGP SRLREQAEVA WRDYAASNGS LGDRLRSDRN
VARAKSRTAL TTLAFVVFGV AVVSIGGLLL VAYRMRRSIV RPLERLSEVV RSRVEGDPSA
FADTHHGADE VRTLARDFNT LTRENARFVA QQGDELRTRQ LVLEVSRGVR QANDVPAALD
GVCRDLGAGL GADRVMLYTL DEGLGVRERS QWHADALPGL PPLPASVARQ VAGVEAELRE
LGGGAVVLPD VFDPEWASDP RVLAFHRATG ARSLVLVPVG SGDQGLDVLA VLSVDQPRWW
QPNEVYAAEQ SAIMLARAIV QLRLAEMREE QVERLMELDH QKTDFMATIS HELRTPLTSI
SGYLELLEDG DFGELNTGQV QALAVVRRNA SRLRGLIEDL LVLNKIESTG LETALDDVPV
ADLVRCVLET MEPAAAGTQV SLVAPPVPDG LTVRADRSQI ERALINLGSN AVKFTPAGGT
VTIDAARADG TVRIRIADTG IGIPEADLTR LAERFFRAGN ATAAAIPGTG LGLAIVRTIV
EGHGGRLDVE STEGEGTTMI VTLPAA
//
