ID W9IWY4_FUSOX Unreviewed; 1023 AA.
AC W9IWY4;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=Exportin-T {ECO:0000256|ARBA:ARBA00018928, ECO:0000256|RuleBase:RU366037};
DE AltName: Full=Exportin(tRNA) {ECO:0000256|RuleBase:RU366037};
DE AltName: Full=tRNA exportin {ECO:0000256|RuleBase:RU366037};
GN ORFNames=FOYG_02592 {ECO:0000313|EMBL:EWY97835.1};
OS Fusarium oxysporum NRRL 32931.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=660029 {ECO:0000313|EMBL:EWY97835.1, ECO:0000313|Proteomes:UP000030753};
RN [1] {ECO:0000313|EMBL:EWY97835.1, ECO:0000313|Proteomes:UP000030753}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FOSC 3-a {ECO:0000313|Proteomes:UP000030753};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusarium oxysporum FOSC 3-a.";
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex. Involved in pre-tRNA
CC splicing, probably by affecting the interaction of pre-tRNA with
CC splicing endonuclease. {ECO:0000256|ARBA:ARBA00025147}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU366037}. Nucleus
CC {ECO:0000256|RuleBase:RU366037}. Note=Shuttles between the nucleus and
CC the cytoplasm. {ECO:0000256|RuleBase:RU366037}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466, ECO:0000256|RuleBase:RU366037}.
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DR EMBL; JH717840; EWY97835.1; -; Genomic_DNA.
DR AlphaFoldDB; W9IWY4; -.
DR HOGENOM; CLU_004414_0_1_1; -.
DR OrthoDB; 2546268at2759; -.
DR Proteomes; UP000030753; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0071528; P:tRNA re-export from nucleus; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR045546; Exportin-T_C.
DR InterPro; IPR040017; XPOT.
DR PANTHER; PTHR15952:SF11; EXPORTIN-T; 1.
DR PANTHER; PTHR15952; EXPORTIN-T/LOS1; 1.
DR Pfam; PF19282; Exportin-T; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|RuleBase:RU366037};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366037};
KW Reference proteome {ECO:0000313|Proteomes:UP000030753};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU366037};
KW Transport {ECO:0000256|RuleBase:RU366037};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555,
KW ECO:0000256|RuleBase:RU366037}.
FT DOMAIN 103..262
FT /note="Exportin-1/Importin-beta-like"
FT /evidence="ECO:0000259|Pfam:PF08389"
FT DOMAIN 337..1021
FT /note="Exportin-T C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19282"
SQ SEQUENCE 1023 AA; 114890 MW; 840FE6727B11E9FF CRC64;
MEAQVENAVG ILSNPTSDQS LKEQAFEYLN QLRNDPSGWQ ACTTLFARTP QTSEVVRMVC
LEVVNYAVHT QGLDQASLAF LKDTLLQYCR QTYGPDAQQE ADPYHLQNKL TQTLTYLFVF
LYQDGWQSFL DDQLELTGLS TNTDNVPGVV FYLRTLGSIH DEIADMLLSR QSNEAKRNTE
LKDQLRAQDM HKVSESWKQL LTRYSNNDTV VELVLKVLGK WVSWMDISLV ISQDMLGLLL
PVVGRPSTDV QDKVRDTAID TLNEICGKKM RSADKMEMIS FINLREIVEQ LVASPPLSEY
KGTSRYDTDL AEAVAKLVNT VLSDIVRALE DNQISDDTRA RANQHLQGFL PFLLRFFSDE
YDEVCSSVIP ALTDLLTFLR KLTVVHQDYG GMLAPILDAI IHKMRYDETT NWGDEDELTD
EAEFQELRRK LQNLQKSIAA IDQPLYMDML SNLVATTFQT LDQQGSQMDW RDLDLALYEM
YLFGELALPN QGLGTKNQPS TEASERLVVM MQKMVESGIA NFSHPAILLQ YMEICVRYCV
VFENHLLQYI PQVLENFVRL VHHDHVRIKT RSWYLFHRFI KQLRAQVGNV AETVIQSIGD
LLPIKAEVPG DDADDDMSSD ESDHSADALF TSQLYLFEAI GCISSTQSTP ADKQALYARS
VMDPLFTDME GHLPRAKSGD AQATLQVHHI VMALGTLAHG FSDWTPGITS ANAHGPPDKA
VSDEFSRAAE AILIALNQLN SSSEIRTACR SAFSKLLGVL GAAVLPQLPQ WIEGLLSQSS
SKDEMAMFLR LLDQVVFGFK AEIYEVLNML LTPLLQRIFG GLTEPIAGTD DEIQLAELRR
EYLSFLQIIL NNGLDGVLVS ESNQGFFEPM ISSIIELAKT LEGNIGGSRL AFTLMTRMAA
IWGGPDVATI SQNPTAPSGS PNPAFPGFDH FMIQRFHSTC WEVMKNPNFR PYQDAQTKQI
LTEIAGLEQT IYTKTGESFI QELQNNIFPS LGVNGDDFLR SLTTSTDKRQ FASYLHNLLK
SRQ
//
