ID   W9J755_FUSOX            Unreviewed;       943 AA.
AC   W9J755;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN   ORFNames=FOYG_00509 {ECO:0000313|EMBL:EWZ00702.1};
OS   Fusarium oxysporum NRRL 32931.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium oxysporum species complex.
OX   NCBI_TaxID=660029 {ECO:0000313|EMBL:EWZ00702.1, ECO:0000313|Proteomes:UP000030753};
RN   [1] {ECO:0000313|EMBL:EWZ00702.1, ECO:0000313|Proteomes:UP000030753}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FOSC 3-a {ECO:0000313|Proteomes:UP000030753}, and NRRL 32931
RC   {ECO:0000313|EMBL:EWZ00702.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA   Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA   Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA   Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA   Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Fusarium oxysporum FOSC 3-a.";
RL   Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EWZ00702.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NRRL 32931 {ECO:0000313|EMBL:EWZ00702.1};
RG   The Broad Institute Genomics Platform;
RA   Ma L.-J., Corby-Kistler H., Broz K., Gale L.R., Jonkers W., O'Donnell K.,
RA   Ploetz R., Steinberg C., Schwartz D.C., VanEtten H., Zhou S., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "Annotation of the Genome Sequence of Fusarium oxysporum NRRL32931.";
RL   Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the importin beta family. Importin beta-2
CC       subfamily. {ECO:0000256|ARBA:ARBA00038423}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JH717839; EWZ00701.1; -; Genomic_DNA.
DR   EMBL; JH717839; EWZ00702.1; -; Genomic_DNA.
DR   HOGENOM; CLU_008136_1_0_1; -.
DR   OrthoDB; 276400at2759; -.
DR   Proteomes; UP000030753; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR040122; Importin_beta.
DR   PANTHER; PTHR10527:SF3; FI21453P1-RELATED; 1.
DR   PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR   Pfam; PF13513; HEAT_EZ; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000030753}.
FT   DOMAIN          33..101
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
FT   REGION          360..403
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        385..402
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   943 AA;  105547 MW;  BDC4C1CC8DCF9F20 CRC64;
     MSSWEPAPDS LQQLAACLKD SLSGFDKSAQ KQADLMLQQA KNSPDINNYL AYLFSSSSPP
     NGLQFSEQDF HLVRSAAGIM LKNNVRSEWK SIPESNLQLI KLAVPMCLQD KNSQIRNFAG
     NIATEIVRRG GLLSWPELLP QLLDLVGNTS GQTSNEAQEG AMSALAKICE DNFRQLTKEV
     NGQRPLNYVL PHFIAATKSP LPKVRAGALT AINVFTPRES QAMLNSIDDL LQHLFVLASD
     DNVDVRRQVC RAFVHLVETR PDKLQPHISG LVDYIISQQK GDDEDLACEA AEFWLAVGEH
     DNLWRALEPY INKIIPVLLE CMVYSGEDIA LLGGASDDEE EEDREEDIRP AFAKKALARK
     ANGEVSESAD QAQNGNGFEK LSGMDDDTEE GEIDDYDDGD DANPDERWTI RKCSAAALDV
     FARDFQSPVF EAIFPYLSQH LKHEEWPQRE AAVLALGAVA DGCMDVVVPH LPELVPYLIS
     LLEDSEPVVR QITCWTLGRY SSWAANLEDT DKDQFFLPLM DGILRHMLDK NKKVQEAAAS
     AFANLEEKAG KILEPYCGPI IQQFVHCFAK YKDRNMYILY DCVQTLAEHI GPAMAAPELS
     GKLMPALIDR YNRVSDQSRE LFPLLECLSY VAMALGDAFA PYAEPIFLRC VNIIHVNLEQ
     TLAAAGNPII DQPDKDFLVT SLDLLSAIVQ ALNDDKSAAL VKSSQQSFFE LLSFCMEDPS
     DEVRQSAYAL LGDCARYVYP LLQPYLATII PILLKQLDMD SVLDEDMDSG FGVVNNACWS
     VGEISMQHKE HMGPWVQELL QRFVEIMTNP RVPKALNENA AMALGRLGLE NSEQLGPHLS
     TFAEEWISIM NEVDATEEKA TAFKGFSMIV GRNPQAMEKE LLNYFTAIAR YRDIDLKSPV
     RQELHDVFQK VIDIYKQIIP EFSNFVGQMQ QRDRQNLESH YTL
//