ID W9QRT7_9ROSA Unreviewed; 234 AA.
AC W9QRT7;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Nicotianamine synthase {ECO:0000256|RuleBase:RU368095};
DE EC=2.5.1.43 {ECO:0000256|RuleBase:RU368095};
GN ORFNames=L484_004285 {ECO:0000313|EMBL:EXB52184.1};
OS Morus notabilis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Moraceae; Moreae; Morus.
OX NCBI_TaxID=981085 {ECO:0000313|EMBL:EXB52184.1, ECO:0000313|Proteomes:UP000030645};
RN [1] {ECO:0000313|Proteomes:UP000030645}
RP NUCLEOTIDE SEQUENCE.
RA He N., Zhao S.;
RT "Draft Genome Sequence of a Mulberry Tree, Morus notabilis C.K. Schneid.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes nicotianamine, a polyamine which serves as a
CC sensor for the physiological iron status within the plant, and/or might
CC be involved in the transport of iron. {ECO:0000256|RuleBase:RU368095}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3 S-adenosyl-L-methionine = 3 H(+) + nicotianamine + 3 S-
CC methyl-5'-thioadenosine; Xref=Rhea:RHEA:16481, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17509, ChEBI:CHEBI:58249, ChEBI:CHEBI:59789; EC=2.5.1.43;
CC Evidence={ECO:0000256|RuleBase:RU368095};
CC -!- SIMILARITY: Belongs to the nicotianamine synthase (NAS)-like family.
CC {ECO:0000256|ARBA:ARBA00007009, ECO:0000256|RuleBase:RU368095}.
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DR EMBL; KE344062; EXB52184.1; -; Genomic_DNA.
DR RefSeq; XP_010092774.1; XM_010094472.1.
DR AlphaFoldDB; W9QRT7; -.
DR eggNOG; ENOG502RDC4; Eukaryota.
DR Proteomes; UP000030645; Unassembled WGS sequence.
DR GO; GO:0030410; F:nicotianamine synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0030418; P:nicotianamine biosynthetic process; IEA:UniProtKB-UniRule.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR004298; Nicotian_synth.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR32266:SF11; NICOTIANAMINE SYNTHASE; 1.
DR PANTHER; PTHR32266; NICOTIANAMINE SYNTHASE 3; 1.
DR Pfam; PF03059; NAS; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51142; NAS; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000030645};
KW S-adenosyl-L-methionine {ECO:0000256|RuleBase:RU368095};
KW Transferase {ECO:0000256|RuleBase:RU368095}.
SQ SEQUENCE 234 AA; 26562 MW; 40CE46ED21AC6CF2 CRC64;
MQLHASILKL ESLRPSKQVN TLFTQLVNLC TLPCSIDVKD LPQELQAKPI NNLNLFPYYN
NYVKLANLEH NILVKNGVLK PKNVAFVGSG PMPLTSLVLA MNHMKFTHFD NYDFDEKANS
LARKIVASDV ELEKRMKFVT KDVMEVKEKL GEYDCIFLAA LVGMNKEKKV KVLGNVRKYM
KEGGILLVRS VKGPRAFLYP VVEEHAFVGF EVLDIFHPSD EVVNSIILVR KPIF
//
