ID W9QWI4_9ROSA Unreviewed; 607 AA.
AC W9QWI4;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=L484_024847 {ECO:0000313|EMBL:EXB56308.1};
OS Morus notabilis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Moraceae; Moreae; Morus.
OX NCBI_TaxID=981085 {ECO:0000313|EMBL:EXB56308.1, ECO:0000313|Proteomes:UP000030645};
RN [1] {ECO:0000313|Proteomes:UP000030645}
RP NUCLEOTIDE SEQUENCE.
RA He N., Zhao S.;
RT "Draft Genome Sequence of a Mulberry Tree, Morus notabilis C.K. Schneid.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EMBL; KE344284; EXB56308.1; -; Genomic_DNA.
DR RefSeq; XP_010094554.1; XM_010096252.1.
DR AlphaFoldDB; W9QWI4; -.
DR STRING; 981085.W9QWI4; -.
DR eggNOG; KOG0167; Eukaryota.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000030645; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd21037; MLKL_NTD; 1.
DR Gene3D; 1.20.930.20; Adaptor protein Cbl, N-terminal domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR036537; Adaptor_Cbl_N_dom_sf.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23315; U BOX DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23315:SF49; U-BOX DOMAIN-CONTAINING PROTEIN 15; 1.
DR Pfam; PF00514; Arm; 3.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00185; ARM; 5.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50176; ARM_REPEAT; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030645};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 277..324
FT /note="U-box"
FT /evidence="ECO:0000259|SMART:SM00504"
FT REPEAT 367..409
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 408..450
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 449..491
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
SQ SEQUENCE 607 AA; 67870 MW; E1B1ABD61211D8EE CRC64;
MAELDQEIIR VDEGTGRENH EAGDDIQSNW NANVLQELVS VVEMAAHFGD YRRTQRKECY
NLVRRMKLLL PLFDELRDLD SPIPDKDIAC LCNLKKALVM ARKLLKTCNE GSKIYLALES
EAIMVRFHTI FDKISQALDD FSYEELGISD EVKEQIELMS MQLRRARKRT DTQDIELAMD
MMVVFSKKDD RNADRAIIER LGKKLDLHSI EDLKIETIVV RNLYREKGGQ NAESIQQIID
LLNKFRQIAG MEETNVIDDP VMPKMLTKSP SLMIPHEFLC PITLEIMTDP VIVASGQWSE
KNNFQLPTKD LPPGHESYSS TSQKEEISSL VEQLSSSHLD SQRKAIKKVR MLSKENPENR
ILIAKSGGIP PLVQLLSYPD SKIQEHAVTA LLNLSIDEAN KKIIAREGAI PAIIQVLEKG
NIEARENSAA ALFSLSIIDE NKMIVGLSNG IPPLVDLLQN GTIRGKKDAA TALFNLSLNQ
ANRTRAISAG IVAPLLQLLK HKNLGMVDEA LSILLLIAAH PDGRQEIGQL SFIETLVDFI
REGAPKNKEC AASVLLELGS NNSSFMLAAL QFGVYKHLVD ITRSGTNRGQ RKANAILKLM
NQSEQIP
//
