ID W9RM57_9ROSA Unreviewed; 529 AA.
AC W9RM57;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=uridine/cytidine kinase {ECO:0000256|ARBA:ARBA00012137};
DE EC=2.7.1.48 {ECO:0000256|ARBA:ARBA00012137};
GN ORFNames=L484_020219 {ECO:0000313|EMBL:EXB97669.1};
OS Morus notabilis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Moraceae; Moreae; Morus.
OX NCBI_TaxID=981085 {ECO:0000313|EMBL:EXB97669.1, ECO:0000313|Proteomes:UP000030645};
RN [1] {ECO:0000313|Proteomes:UP000030645}
RP NUCLEOTIDE SEQUENCE.
RA He N., Zhao S.;
RT "Draft Genome Sequence of a Mulberry Tree, Morus notabilis C.K. Schneid.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via salvage pathway;
CC UMP from uridine: step 1/1. {ECO:0000256|ARBA:ARBA00004690}.
CC -!- SIMILARITY: In the C-terminal section; belongs to the UPRTase family.
CC {ECO:0000256|ARBA:ARBA00010723}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the uridine kinase
CC family. {ECO:0000256|ARBA:ARBA00008173}.
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DR EMBL; KE345280; EXB97669.1; -; Genomic_DNA.
DR RefSeq; XP_010103966.1; XM_010105664.1.
DR AlphaFoldDB; W9RM57; -.
DR STRING; 981085.W9RM57; -.
DR eggNOG; KOG4203; Eukaryota.
DR UniPathway; UPA00574; UER00637.
DR Proteomes; UP000030645; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0004845; F:uracil phosphoribosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0004849; F:uridine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0044206; P:UMP salvage; IEA:UniProtKB-UniPathway.
DR CDD; cd06223; PRTases_typeI; 1.
DR CDD; cd02023; UMPK; 1.
DR Gene3D; 3.40.50.2020; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR006083; PRK/URK.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR000764; Uridine_kinase-like.
DR PANTHER; PTHR10285; URIDINE KINASE; 1.
DR PANTHER; PTHR10285:SF97; URIDINE KINASE-LIKE PROTEIN 3; 1.
DR Pfam; PF00485; PRK; 1.
DR Pfam; PF14681; UPRTase; 1.
DR PRINTS; PR00988; URIDINKINASE.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53271; PRTase-like; 1.
PE 3: Inferred from homology;
KW Allosteric enzyme {ECO:0000256|ARBA:ARBA00022533};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EXB97669.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030645};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 94..295
FT /note="Phosphoribulokinase/uridine kinase"
FT /evidence="ECO:0000259|Pfam:PF00485"
SQ SEQUENCE 529 AA; 59230 MW; BA0E6F8789A8473F CRC64;
MSAALSSSQG RPNWSTDLFS TGRLVEMNLY VTSRPVDIRS MAMDSKSVVD LIEASSGVHF
SGFHMNGLVE QRHSSEVEQP TTSATENLHM QPFVIGVAGG AASGKTTVCD MIIQQLHDQR
VVLVNQDSFY HNLTGEELAR VQDYNFDHPD AFDTEKLLAS MDKLRNGKAV DIPKYDFKSY
KNNVFPPRRV NPSDVIILEG ILIFHDPRVR ELMNMKIFVD TGLLSLDTSH CKISSADADV
RLARRIRRDT VEKHRDIGAV LDQYSKFVKP AFDDFILPTK KYADIIIPRG GDNHVAIDLI
VQHIRTKLGQ HDLCKIYPNL YVIQSTFQIR GMHTLIRDSQ TTKHDFVFYA DRLIRLVVEH
GLGHLPFTEK QVLTPTGSVY TGVDFCKRLC GVSVIRSGES MENALRACCK GIKIGKILIH
REGDNGQQLI YEKLPQDISE RHVLLLDPIL GTGNSAVQAI SLLLKKGVPE SNIIFLNLIS
APQGIHVVCK SFPRIKIVTS EIEIGLNEDF RVIPGMGEFG DRYFGTDDN
//
