ID W9RN64_9ROSA Unreviewed; 650 AA.
AC W9RN64;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Cysteine-rich receptor-like protein kinase 2 {ECO:0000313|EMBL:EXB82556.1};
GN ORFNames=L484_027733 {ECO:0000313|EMBL:EXB82556.1};
OS Morus notabilis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Moraceae; Moreae; Morus.
OX NCBI_TaxID=981085 {ECO:0000313|EMBL:EXB82556.1, ECO:0000313|Proteomes:UP000030645};
RN [1] {ECO:0000313|Proteomes:UP000030645}
RP NUCLEOTIDE SEQUENCE.
RA He N., Zhao S.;
RT "Draft Genome Sequence of a Mulberry Tree, Morus notabilis C.K. Schneid.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR EMBL; KE344869; EXB82556.1; -; Genomic_DNA.
DR RefSeq; XP_010100422.1; XM_010102120.1.
DR AlphaFoldDB; W9RN64; -.
DR STRING; 981085.W9RN64; -.
DR GeneID; 21410342; -.
DR KEGG; mnt:21410342; -.
DR eggNOG; ENOG502QRU4; Eukaryota.
DR OrthoDB; 1039691at2759; -.
DR Proteomes; UP000030645; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 3.30.430.20; Gnk2 domain, C-X8-C-X2-C motif; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR002902; GNK2.
DR InterPro; IPR038408; GNK2_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR47973:SF2; CYSTEINE-RICH RECEPTOR-LIKE PROTEIN KINASE 2; 1.
DR PANTHER; PTHR47973; CYSTEINE-RICH RECEPTOR-LIKE PROTEIN KINASE 3; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF01657; Stress-antifung; 2.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51473; GNK2; 2.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EXB82556.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Receptor {ECO:0000313|EMBL:EXB82556.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000030645};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..650
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004932681"
FT TRANSMEM 254..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..130
FT /note="Gnk2-homologous"
FT /evidence="ECO:0000259|PROSITE:PS51473"
FT DOMAIN 135..240
FT /note="Gnk2-homologous"
FT /evidence="ECO:0000259|PROSITE:PS51473"
FT DOMAIN 320..613
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 348
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 650 AA; 72392 MW; A18BC6006BC3B05C CRC64;
MTIPSLLLHT ILLLNTLLLL QTIWADPRAQ TVNITCGTVR EHNTTIFVQN FVAVMEKISE
QMRTHGFGQA LVGTGPDANY GLAQCYGDLS LLDCVLCYAE ARTVLPQCFP YNSGRIFLDG
CFMRAGNYSF YEEYKGPEDM TVCGNATRKG SVFGESARQA VAQAVAAAGA PSITRGYAKA
KVAVRNETAY VLADCWRSLN QSSCSKCLDN ASRSIVKCLP WSEGRALNTG CFMRYSDRDF
LNKEAGSGSS RASWVVIVVS VVSSVVVLVV GVAIGHHIWK RRYIQKKRRG SDVAKKMVKT
LNDSSLNFKY ATLEKATGSF DDSNKLGQGG FGSVYKGVLP DGREIAVKRL FFNNKHRVAD
FYNEVNIISS VEHKNLVRLL GCSCSGPESL LVYEYLPNKS LDRFIFDQTR GKGLNWEKRY
EIIIGTAEGL VYLHENSKIR IIHRDIKTSN ILLDSRLRAK IADFGLARSF EEDKSHISTA
IAGTLGYMAP EYLAHGQLTE KVDVYSFGVL LLEIVTGRQN NRSKTSEYTD SLVTLTWKHF
QSGKAEELYD PNLMLHNYRD SQNQIKNQIS RVVHIGLLCT QEIGSLRPTM SKALQMLTKK
EQQLPAPTSP PFIDEKTMEF NDTCEDPSYP LNGDDAGSVA NFTHSSFYPR
//
