ID W9RSS7_9ROSA Unreviewed; 686 AA.
AC W9RSS7;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=(R)-mandelonitrile lyase {ECO:0000256|ARBA:ARBA00013074};
DE EC=4.1.2.10 {ECO:0000256|ARBA:ARBA00013074};
GN ORFNames=L484_022863 {ECO:0000313|EMBL:EXB94551.1};
OS Morus notabilis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Moraceae; Moreae; Morus.
OX NCBI_TaxID=981085 {ECO:0000313|EMBL:EXB94551.1, ECO:0000313|Proteomes:UP000030645};
RN [1] {ECO:0000313|Proteomes:UP000030645}
RP NUCLEOTIDE SEQUENCE.
RA He N., Zhao S.;
RT "Draft Genome Sequence of a Mulberry Tree, Morus notabilis C.K. Schneid.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(R)-mandelonitrile = benzaldehyde + hydrogen cyanide;
CC Xref=Rhea:RHEA:18313, ChEBI:CHEBI:17169, ChEBI:CHEBI:18407,
CC ChEBI:CHEBI:18450; EC=4.1.2.10;
CC Evidence={ECO:0000256|ARBA:ARBA00001147};
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
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DR EMBL; KE345164; EXB94551.1; -; Genomic_DNA.
DR RefSeq; XP_010102984.1; XM_010104682.1.
DR AlphaFoldDB; W9RSS7; -.
DR STRING; 981085.W9RSS7; -.
DR eggNOG; KOG1238; Eukaryota.
DR Proteomes; UP000030645; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0046593; F:mandelonitrile lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.30.410.40; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR45968:SF23; GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45968; OSJNBA0019K04.7 PROTEIN; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:EXB94551.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000030645};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 257..271
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
SQ SEQUENCE 686 AA; 74096 MW; 41E6A862DB3B4E31 CRC64;
MICADFSYMK VVSNATNLPR SAEYDYIVIG GGTAGCPLAA TLSRNYSVLL LERGSAPSTY
PEVLQADQAE ANLLNDDDGK NPVQKFKSEE GVEIARGRVL GGSSMINIGF YSRAEKEFYP
KSGINWDSDV VEKAYQWVEE TIVHRSDLLP WQSTFKDALL EAGLVPDNGF TLEHIVGTKA
SGSLFDGLGR RHGAVELLNR GDFRNLRVAV RASVEKILFT RTKRGGLAAN GVQYRDSRGM
PHRAFVRAKG EVILSAGAIG SPQLLLLSGV GPVSDLSSQL IPVVQPQPDV GKFMADNPRS
NIGIVVPFSL NASYAQVVGI ATDFYIESLS TIKPFASLTK PSGVYGNIST PIDLSVVFLA
NKVPGPLSIG SLALASRNNV SVGPKVRFNY FSEPEDLARC VKGMRKVGDM LRTKAFAALK
FDKNAQGENG FKFVGPTLPV NYRTDNSSLE AFCRSNITTW WHYHGGCRVG KVVDGDFRFT
GINALRVVDG SVFTSSPGTN PQATLMMIGR LSCCYYYCCG CCCCCCYYYY YDYCCCCCYY
YYCCCCCYCY YYYCDYYYYC CCCCCCYYYY YYYNCYAAVV VTTATAPTAA ATTTAPTAAT
THTTVTTATA TTVTTATATA ATATIAATAT TTTSATTATT TASTTATTAT TATATTTAAP
TATTVTTAIV AATTTKCTFT YATTNR
//
