ID W9RYJ5_9ROSA Unreviewed; 960 AA.
AC W9RYJ5;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=E3 SUMO-protein ligase SIZ1 {ECO:0000313|EMBL:EXB98564.1};
GN ORFNames=L484_014406 {ECO:0000313|EMBL:EXB98564.1};
OS Morus notabilis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Moraceae; Moreae; Morus.
OX NCBI_TaxID=981085 {ECO:0000313|EMBL:EXB98564.1, ECO:0000313|Proteomes:UP000030645};
RN [1] {ECO:0000313|Proteomes:UP000030645}
RP NUCLEOTIDE SEQUENCE.
RA He N., Zhao S.;
RT "Draft Genome Sequence of a Mulberry Tree, Morus notabilis C.K. Schneid.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Protein modification; protein sumoylation.
CC {ECO:0000256|ARBA:ARBA00004718}.
CC -!- SIMILARITY: Belongs to the PIAS family.
CC {ECO:0000256|ARBA:ARBA00005383}.
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DR EMBL; KE345290; EXB98564.1; -; Genomic_DNA.
DR RefSeq; XP_010104123.1; XM_010105821.1.
DR AlphaFoldDB; W9RYJ5; -.
DR STRING; 981085.W9RYJ5; -.
DR eggNOG; KOG2169; Eukaryota.
DR UniPathway; UPA00886; -.
DR Proteomes; UP000030645; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0019789; F:SUMO transferase activity; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016925; P:protein sumoylation; IEA:UniProtKB-UniPathway.
DR CDD; cd15570; PHD_Bye1p_SIZ1_like; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR004181; Znf_MIZ.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10782:SF4; E3 SUMO-PROTEIN LIGASE SIZ1; 1.
DR PANTHER; PTHR10782; ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF02037; SAP; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS50800; SAP; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS51044; ZF_SP_RING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:EXB98564.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000030645};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00452}.
FT DOMAIN 69..103
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT DOMAIN 405..477
FT /note="SP-RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51044"
FT REGION 841..864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 887..915
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 846..862
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 960 AA; 105761 MW; 6215A5BC2D215B41 CRC64;
MSNCNAFQVS RKLEPGNPAL EQKYHDKPTT YFLSRRLPRD LVLQKNQHFV SCIGPGSERL
YALVSSDKLA YFRIKELKDV LTHLGLSKQG KKQDLVDRIL TILSDDQVSK MWAKKNAVRK
EQVAQLVDDI YRKMQVSTAT DLASKAQGVS DSSNVKVKVE NDDRSFQSET KIRCVCGNQL
ETESMIQCED RNCQVWQHIN CVIIPDKPME GSTPYPDPFY CELCRLSRAD PFWHQLGHPL
PPVKLITTNI PTDGTNPVQS VERTFQLQRS DKELTLKQEF DVQAWCMLLN DKVSFRMQWP
QYADLQVNGI PVRAINRPGS QLLGANGRDD GPIITTYLKE GLNKISLTGC DARVFCLGVR
LVKRQTVQKI LSLIPKESEG EQFEDAVARV RRCVGGGTAT DDADSDSDLE VVADSFVVNL
RCPMSGSRMK VAGRFKPCAH MGCFDLEWQC PICLKNYSLE YIITDPYFNR ITSMMRHCGE
DATEIEVKPD GSWRVKAKSE SERRELGDLG QWHFPDGTIW LPAGGDVKAK TEMKQVKQEG
ISDSHPGLKL GIKKNSNGFW EVSKPDDMNN SIDNGLQDGL GNYEQKVIPM SSSATGSCRD
GEDPSVNQDG GGNFDFTNNG VEMDSLTLNV DSMYGITEQA PPVPIRNSEV IEISDSDDDD
LFISPRSVYK NHPNDGSGVP FSVSPPVIPD SYAEDPAGGT SCLGLFNGND DEFGIPPLWH
LPPGNQAGPG FQFFGSEAEV SDALVDLQHG SINCSSSMNG YTLAPETVTG SAPLVQNSSV
GRSDTDMNDG LVDNPLAFAG DDPSLQIFLP TNPTNASAQS DFRDRADVSN GVRTEDWISL
RLGGSAGGTN GESATPSGLN SKLQVPARDG AMNSMADHAS LLLGMNDGRP EKGIRQRSDS
PFTFPRQKRS MQRHPWWKEK VENKNGGTEL APAKFLESVS SEFPSALSSL KFAMYLLTGS
//
