ID W9VF81_9EURO Unreviewed; 1059 AA.
AC W9VF81;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 13-SEP-2023, entry version 38.
DE RecName: Full=Cytoskeleton assembly control protein Sla2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=A1O7_09625 {ECO:0000313|EMBL:EXJ54287.1};
OS Cladophialophora yegresii CBS 114405.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=1182544 {ECO:0000313|EMBL:EXJ54287.1, ECO:0000313|Proteomes:UP000019473};
RN [1] {ECO:0000313|EMBL:EXJ54287.1, ECO:0000313|Proteomes:UP000019473}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 114405 {ECO:0000313|EMBL:EXJ54287.1,
RC ECO:0000313|Proteomes:UP000019473};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora yegresii CBS 114405.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the SLA2 family.
CC {ECO:0000256|ARBA:ARBA00010135}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ54287.1}.
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DR EMBL; AMGW01000007; EXJ54287.1; -; Genomic_DNA.
DR RefSeq; XP_007761802.1; XM_007763612.1.
DR AlphaFoldDB; W9VF81; -.
DR STRING; 1182544.W9VF81; -.
DR GeneID; 19184187; -.
DR VEuPathDB; FungiDB:A1O7_09625; -.
DR eggNOG; KOG0980; Eukaryota.
DR HOGENOM; CLU_004601_0_0_1; -.
DR OrthoDB; 7775at2759; -.
DR Proteomes; UP000019473; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR CDD; cd17007; ANTH_N_Sla2p; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 1.20.1410.10; I/LWEQ domain; 1.
DR InterPro; IPR011417; ANTH_dom.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR035964; I/LWEQ_dom_sf.
DR InterPro; IPR002558; ILWEQ_dom.
DR InterPro; IPR030224; Sla2_fam.
DR PANTHER; PTHR10407; HUNTINGTIN INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR10407:SF15; HUNTINGTIN INTERACTING PROTEIN 1; 1.
DR Pfam; PF07651; ANTH; 1.
DR Pfam; PF01608; I_LWEQ; 1.
DR SMART; SM00273; ENTH; 1.
DR SMART; SM00307; ILWEQ; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF109885; I/LWEQ domain; 1.
DR PROSITE; PS50942; ENTH; 1.
DR PROSITE; PS50945; I_LWEQ; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000019473}.
FT DOMAIN 15..144
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT DOMAIN 816..1059
FT /note="I/LWEQ"
FT /evidence="ECO:0000259|PROSITE:PS50945"
FT REGION 270..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 314..627
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1018..1054
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 275..296
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1059 AA; 119999 MW; 3D5B54D00B115EBC CRC64;
MAYPALATGT GRNIDMAKTE SDLAINIRKA TSIEETAPKR KHVRSCIVYT WDHRSSLSFW
AGMKVQPVMA DEVQTFKALI TIHKVLQEGH PVTVKEAQQN VNWIESLARG AMGEGLRGYG
PLIREYVFFL LAKLGFHRNH PEFNGLFEYE EYISLKSIND PNEGYETISD LMTLQDQIDT
FQKLIFSHFR GGANNECRIA ALVPLVQESY GIYKFITSML RAMHTTTGDD EALEPLRTRY
DGQHYRLVKF YYECSNLRYL TSLITVPKLP QDPPNLLSED DEKPALPRRP AKEIEKPPSP
VAKNGTPDNQ KDIEDFWTKE AQRQQQEYEA EQRRLAQQWE DQQRQQMAAQ QEAQRQFEEQ
QRLQAEQQRL AQEQLLRDQY AAQTQGRMAE LERENLNARA QYERDQLMLQ QYDQRMKALE
EQLQQLNNNY QLQSQSKDDQ ITSLQEQVNT WRSKYEALAK LYSQLRQEHL DLLQTTKSLK
LKAASAQEAI ERRERLEREM KTKNLELADM IRERDRALHE RDRAQGSNRE EVEKLKRELR
LAVDRADDAE RAKGSEISSL LAKYNREMAD LEEAVRSKTR QLEDLRAKQG ERSYDHEAAL
KEKDDEIEIY KSGMEQALEE LEELKLGHGE SDGALDTAID EVIKTNVNKI NDIIDSVLQS
GVQRVDDAIY ELDSPMQAGN QNATAPYVLS QVEKASASAT EFSTAFNNFV ADGPGSDHAD
IIKTVSVFAA SIADVLSNTK GLTRFATEEK KGDELTNAAR QSALSTIQFF RNLQSFRLEG
LEPMQKSDVV INSNHDVLMK LQRLSKLADA FAPKGSKIST TGDIGDLVDN ELTKAANAIE
AAAQRLAKMK NKPRDGYSTY ELKVNDTILE AAIAITNAIA QLIKAATESQ NEIVREGRGS
SSRTAFYKKN NRWTEGLISA AKAVATSTNT LIETADGVIS GRNSPEQLIV ASNDVAASTA
QLVAASRVKA SFMSQTQDRL EQASRAVGAA CRSLVRQVQD IIRQKARDDG DREDYSTLSG
HEFKVREMEQ QVEILQLRNA LEAAQARLTE MRKLSYRED
//
