ID W9W1M7_9EURO Unreviewed; 359 AA.
AC W9W1M7;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Histidine-specific methyltransferase SAM-dependent domain-containing protein {ECO:0000259|Pfam:PF10017};
GN ORFNames=A1O7_06310 {ECO:0000313|EMBL:EXJ58880.1};
OS Cladophialophora yegresii CBS 114405.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=1182544 {ECO:0000313|EMBL:EXJ58880.1, ECO:0000313|Proteomes:UP000019473};
RN [1] {ECO:0000313|EMBL:EXJ58880.1, ECO:0000313|Proteomes:UP000019473}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 114405 {ECO:0000313|EMBL:EXJ58880.1,
RC ECO:0000313|Proteomes:UP000019473};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora yegresii CBS 114405.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC {ECO:0000256|ARBA:ARBA00008361}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ58880.1}.
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DR EMBL; AMGW01000004; EXJ58880.1; -; Genomic_DNA.
DR RefSeq; XP_007758503.1; XM_007760313.1.
DR AlphaFoldDB; W9W1M7; -.
DR STRING; 1182544.W9W1M7; -.
DR GeneID; 19180888; -.
DR VEuPathDB; FungiDB:A1O7_06310; -.
DR eggNOG; ENOG502QS9T; Eukaryota.
DR HOGENOM; CLU_049766_0_2_1; -.
DR OrthoDB; 45787at2759; -.
DR Proteomes; UP000019473; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR019257; MeTrfase_dom.
DR InterPro; IPR017804; MeTrfase_EgtD-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR017805; SAM_MeTrfase_EasF-type_put.
DR NCBIfam; TIGR03439; methyl_EasF; 1.
DR PANTHER; PTHR43397; ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1; 1.
DR PANTHER; PTHR43397:SF2; HISTIDINE-SPECIFIC METHYLTRANSFERASE SAM-DEPENDENT DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF10017; Methyltransf_33; 1.
DR PIRSF; PIRSF018005; UCP018005; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000019473};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 24..330
FT /note="Histidine-specific methyltransferase SAM-dependent"
FT /evidence="ECO:0000259|Pfam:PF10017"
SQ SEQUENCE 359 AA; 40564 MW; FEDB060E081DCFE8 CRC64;
MGSYEEPSPD IIDIQSDAEK IELSKDTAEC LKTEPSSFSS LLLWNEQGLK RFEAVTYARE
YYLTNSEIEL LKAHSHKIAD TIESGSIVVE LGSGALRKTK ILLQALDDAK KPVDYFALDL
SRAELERTLK EVSPGTFEHV RCHGLLGTYD DGLVWLQQYE IASRPRVVLS LGSTLGSFTR
PEAADFFRAF GAAIDHAVNG AIRSEPLMVI GADGCKKAER VWAAYNDAEG RNDSFIRNAL
DHANQILGKR IFHQDEWDRQ GQWNDELGRH EQYLVPRKDV WFEDRCLKAG EKIFVVASHK
YDDKDREELW KGAGLKLLDG WQVPETQYGR SLPSSRDDTL ISMQGYIFCR RGGQTLPES
//
