ID W9W1P9_9EURO Unreviewed; 312 AA.
AC W9W1P9;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Enoyl-CoA hydratase domain-containing protein 3, mitochondrial {ECO:0000256|ARBA:ARBA00040545};
GN ORFNames=A1O7_02288 {ECO:0000313|EMBL:EXJ61858.1};
OS Cladophialophora yegresii CBS 114405.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=1182544 {ECO:0000313|EMBL:EXJ61858.1, ECO:0000313|Proteomes:UP000019473};
RN [1] {ECO:0000313|EMBL:EXJ61858.1, ECO:0000313|Proteomes:UP000019473}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 114405 {ECO:0000313|EMBL:EXJ61858.1,
RC ECO:0000313|Proteomes:UP000019473};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora yegresii CBS 114405.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May play a role in fatty acid biosynthesis and insulin
CC sensitivity. {ECO:0000256|ARBA:ARBA00037410}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|RuleBase:RU003707}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ61858.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMGW01000002; EXJ61858.1; -; Genomic_DNA.
DR RefSeq; XP_007754512.1; XM_007756322.1.
DR AlphaFoldDB; W9W1P9; -.
DR GeneID; 19176897; -.
DR VEuPathDB; FungiDB:A1O7_02288; -.
DR eggNOG; KOG1682; Eukaryota.
DR HOGENOM; CLU_009834_1_0_1; -.
DR OrthoDB; 2421075at2759; -.
DR Proteomes; UP000019473; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd06558; crotonase-like; 1.
DR Gene3D; 1.10.12.10; Lyase 2-enoyl-coa Hydratase, Chain A, domain 2; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR InterPro; IPR014748; Enoyl-CoA_hydra_C.
DR PANTHER; PTHR43602; -; 1.
DR PANTHER; PTHR43602:SF1; ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL; 1.
DR Pfam; PF00378; ECH_1; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
PE 3: Inferred from homology;
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000019473};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
SQ SEQUENCE 312 AA; 33770 MW; A00033F4AF68A4CC CRC64;
MSWPKLPSRV AYLALRNGRR RNALSLAVLR DLRSQLHAYN TSPADGCLRI LPPFQPGILS
ELESAVKNGN PDARNQYDWL LEADKWQEHR GELPKVIVLR SEGTVFSSGH DLSELRALSH
DEVKETFRLC AEVMSLIRRS PAPVIGVIQG LATAAGAQLA LTTDLPIAAA TTHFRLPGAS
IGLPCTSPST AASRRLGHAF TYRMLALAEP VRADQLPGGA VEVVADEEAL ERRVASTVSQ
LSQTIAGQPQ ALGKWGYWTQ LGLNGATSAQ GGDGYEDAVS WTGRLMALHA RSADANEGIN
AFFEKRTPSW KT
//
