ID W9W3J3_9EURO Unreviewed; 1763 AA.
AC W9W3J3;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EXJ62627.1};
GN ORFNames=A1O7_03065 {ECO:0000313|EMBL:EXJ62627.1};
OS Cladophialophora yegresii CBS 114405.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=1182544 {ECO:0000313|EMBL:EXJ62627.1, ECO:0000313|Proteomes:UP000019473};
RN [1] {ECO:0000313|EMBL:EXJ62627.1, ECO:0000313|Proteomes:UP000019473}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 114405 {ECO:0000313|EMBL:EXJ62627.1,
RC ECO:0000313|Proteomes:UP000019473};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora yegresii CBS 114405.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ62627.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMGW01000002; EXJ62627.1; -; Genomic_DNA.
DR RefSeq; XP_007755281.1; XM_007757091.1.
DR STRING; 1182544.W9W3J3; -.
DR GeneID; 19177666; -.
DR VEuPathDB; FungiDB:A1O7_03065; -.
DR eggNOG; KOG4305; Eukaryota.
DR HOGENOM; CLU_001083_2_0_1; -.
DR OrthoDB; 2734900at2759; -.
DR Proteomes; UP000019473; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001180; CNH_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR46572; RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46572:SF1; RHO1 GUANINE NUCLEOTIDE EXCHANGE FACTOR TUS1; 1.
DR Pfam; PF00780; CNH; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00036; CNH; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50219; CNH; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Reference proteome {ECO:0000313|Proteomes:UP000019473};
KW Transferase {ECO:0000256|ARBA:ARBA00022676}.
FT DOMAIN 920..1112
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 1149..1328
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 1393..1707
FT /note="CNH"
FT /evidence="ECO:0000259|PROSITE:PS50219"
FT REGION 1..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 112..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 369..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 445..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 538..721
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1235..1277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..62
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..153
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 169..189
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..291
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 388..413
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..488
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 538..577
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 650..681
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 688..710
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1240..1277
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1763 AA; 195213 MW; 1380C015705B24A2 CRC64;
MASYQSNGQS SPYYTSNNHP SASQNVPYGS QSTYPPQPLQ RTPSFDAGDD ERYLDGEHDP
RWGAQRYASY AAPTAGASPH VNRSQSASIQ SSVAAPFRSN TQHAALAGYQ HQYQTPSVPA
HAPYNPAQYH QQPQNTYNPQ PYTTPQSAHP TSAYQPYVPA AYGSPDLARR TSGFNSYGSY
DANSHYTYSS SQPPPPPRSD TVRFPDPQAY GAYQHDIAQQ YPVQHQQVLS PYSPPAPAPP
PHGRNSSTPE EQYPYPTGSS VAYSSLSAYS SPDINRNSSF ASHVSARSAS PQPSIPTPPS
RQPSNRSPQR MNTLGRHPEG RSLPGLPSEP ESDSDYFTGA DRRSSAVNTR SAGYDDLMGE
LDDAIGQSSR HIRAGSDVRL RHSRDGGQDV QGQPSPQPLL SPDETPTHLN GNIASTGNTY
INYGAFSDDS DAEAAAGLAA MQALDEQERA EDERRRSGSA TLFPSQPHSH DAGARLSSQE
QSSDSDYAGY GDLSLAGGGY APDMSYGEQV VSNYAAAATA MPQAELYGRL NTRMDSVRSS
AVSSEGRESM TSGFESIPSA QSHHPFSPSQ NVARVDTGGT GGLTEPSPHP RRLSYEDGDE
STLIDAEAGR ASASSSPRDD MPDLFFHPGM SQQRPLPPPP SHSDPGLRLP HSLPSSTHTQ
QSRFSHYDQS NTRSYPTAPD AYPNSLLSPI TVPRSTSLSS TRSAPKVTEQ VYRSKTDADR
QRMLRQQGRT MSDLYDIASP QSAMALDLPA IPKKRYNPSK LTNDQFKRCL EPWALSSILD
WIKELAEEEV DLKEANIAEG IIALFMNKVP TMYITEAEAL GERVVKAMLD ANALVKDEEW
VKFGPGTLSG VLYQLTGSGC YSSKLHLYHT KGRCYSYHCM RTLKRLDLDA LPVEKKSEDW
ATFYKLKKED IETHDKKEIE RQNVLHEIVT SEDVFISQLD VLRELYRDRL AAANPSIIPT
KKLQNFLNEV FGGVDKVKKV NQDYLLGQLK YRQTEQGPWI VGFSDIFREW IRKARPVYVE
YASNFPRADC LMRREAERNI PFKSFLDQAR ENKRSNRLGW DNFLKAPITR LQRYSLLLAT
VQKNMLKDSE EKNSLAFALD EIRAATFECD SKFAEMTKKM ELIEMQTKLR LRPPMEKEVE
LNLDHLGREI VFRGELQRAG GKGFQWVDTH AILFDHYLVL AKPLARDRRE GYYDVSKVPI
PMDLLVLESS NDPAVVKSSM KGIGAVTTVA VPRGQVAPDT RLNRAQSTAS GGTPGPLTHT
STNLSIGSGN TSQSMVPITT LDSGNSKEEK IMYPFRVKHL GKTETYTLYA PSAQNRQDWC
EAIIQAKTRH AESLHQQNAE PFKMRVLADT AFAYEGLTYP AKRILIKGTP LDRAVQEAEK
MFEGQGRPAP VCRAPVNCAT VFNQPYGRLM CAVGTDYGVY ISEYQNSRGW VRAIQMQRVT
QIAVLEEFNL FLLISDKALI AYHLDVVCPP TGNPVAQNDA SSRKAPQKLS GSKDIGFFVT
GRMKERTLVF YKKRDGIAST FKVLEPVLQK NTTSRSRFLP SSTRRGQTEF FREYDEFYIP
AECYGLNLFQ SSLAISTARG VEVLTLEKKQ TWSVPNLRSE EAATQAHLSS IASRIKDLKP
LGMFRLGEAE FLVTFEECAV YVNKHGDISR GVVMEFVGRA KAACLYNQYL ILVDDDFVEI
RDAQNGRLKQ VIAGKDIRLL DDGGGGSGGA QTQPQAMLGG GLNGLGLKNF GNAPRTPKLV
LQHPEYERSH VVVELLLTTD VAQ
//
