ID W9W5D3_9EURO Unreviewed; 680 AA.
AC W9W5D3;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
GN ORFNames=A1O5_13023 {ECO:0000313|EMBL:EXJ53774.1};
OS Cladophialophora psammophila CBS 110553.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=1182543 {ECO:0000313|EMBL:EXJ53774.1, ECO:0000313|Proteomes:UP000019471};
RN [1] {ECO:0000313|EMBL:EXJ53774.1, ECO:0000313|Proteomes:UP000019471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 110553 {ECO:0000313|EMBL:EXJ53774.1,
RC ECO:0000313|Proteomes:UP000019471};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora psammophila CBS 110553.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ53774.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMGX01000040; EXJ53774.1; -; Genomic_DNA.
DR RefSeq; XP_007751782.1; XM_007753592.1.
DR AlphaFoldDB; W9W5D3; -.
DR STRING; 1182543.W9W5D3; -.
DR GeneID; 19197709; -.
DR eggNOG; KOG4269; Eukaryota.
DR HOGENOM; CLU_017095_2_0_1; -.
DR OrthoDB; 1359393at2759; -.
DR Proteomes; UP000019471; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23176:SF125; GTPASE ACTIVATOR (BEM2), PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04450)-RELATED; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000019471}.
FT DOMAIN 369..566
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 576..680
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..42
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..78
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..95
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..121
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..149
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 230..257
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..283
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..298
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 624..647
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 680 AA; 75094 MW; 2C6BB9CE34934709 CRC64;
MPKASALPHL NLAPENNEEL NGLTPATLSP RSTGSPHTPR SAPTSPYLRG PPPSFMSHQA
SVSQDSPNDG SRTGPSSPRI TAMPEFPPSP VPQSPKHGRD PSKGFFSNLM ASKSSHKLHA
SETSIPEGAE KPNGRSRASS KERSLHSVKK QGSTPDLPKA GSGSGPINDN EPPASSESIP
SQPSLEPVLA AKKTKSKFGG ILARTKTVKM EEITPKQKHP PPSHLQLDTS NVGKDHDDTS
PRTAPIKLEH RERAFGPEGN ASVRNRSVDR QTQTRDDSQS IKRDRQTGNI PMSHSFRDGS
TLQILSNLGQ TGKGVGDRLG KAGKGFFGKI TRSGSSNERE VLTVTDDNYV CTTINLPLVK
QTRKTRIARR LELSKDKTEF WMPALPWRCI DYLNMNGAEE EGLYRIPGSG RDVKHWQRRF
DTEFDINLFD EPDLYDINTI GSMFKSWLRE LPDEILPKSV QNKIATQCAG ATSAPQLLRD
ELSRLPPFNY YLLFAITCHL SLLNSYAEKN KMDYRNLCIC FQPCLKIDAF CFQFLVMDWK
NCWQGCWTEK EYLEEEYRYE REGSVNESED LAVDERAISS SGSSQQQQPP PPPAAADRQV
SAQQPVPPRS ADAAAHRKSM APRTKQRSLS QGGSARDRSN SAHAPSQSVP AVPRMVTPEP
PKLSLDQKLP ELTGLSPIRM
//
