ID W9WCX4_9EURO Unreviewed; 127 AA.
AC W9WCX4;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Cytochrome b5 heme-binding domain-containing protein {ECO:0000259|PROSITE:PS50255};
GN ORFNames=A1O5_10943 {ECO:0000313|EMBL:EXJ65967.1};
OS Cladophialophora psammophila CBS 110553.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=1182543 {ECO:0000313|EMBL:EXJ65967.1, ECO:0000313|Proteomes:UP000019471};
RN [1] {ECO:0000313|EMBL:EXJ65967.1, ECO:0000313|Proteomes:UP000019471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 110553 {ECO:0000313|EMBL:EXJ65967.1,
RC ECO:0000313|Proteomes:UP000019471};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora psammophila CBS 110553.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Membrane bound hemoprotein which function as an electron
CC carrier for several membrane bound oxygenases.
CC {ECO:0000256|ARBA:ARBA00043840}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004131}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004131}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004131}. Microsome membrane
CC {ECO:0000256|ARBA:ARBA00037877}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00037877}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00037877}.
CC -!- SIMILARITY: Belongs to the cytochrome b5 family.
CC {ECO:0000256|ARBA:ARBA00038168, ECO:0000256|RuleBase:RU362121}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ65967.1}.
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DR EMBL; AMGX01000022; EXJ65967.1; -; Genomic_DNA.
DR RefSeq; XP_007749707.1; XM_007751517.1.
DR AlphaFoldDB; W9WCX4; -.
DR STRING; 1182543.W9WCX4; -.
DR GeneID; 19195634; -.
DR HOGENOM; CLU_1970323_0_0_1; -.
DR OrthoDB; 2712490at2759; -.
DR Proteomes; UP000019471; Unassembled WGS sequence.
DR GO; GO:0020037; F:heme binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd.
DR InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR InterPro; IPR018506; Cyt_B5_heme-BS.
DR PANTHER; PTHR19359; CYTOCHROME B5; 1.
DR PANTHER; PTHR19359:SF14; CYTOCHROME B5-RELATED; 1.
DR Pfam; PF00173; Cyt-b5; 1.
DR PRINTS; PR00363; CYTOCHROMEB5.
DR SMART; SM01117; Cyt-b5; 1.
DR SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
DR PROSITE; PS00191; CYTOCHROME_B5_1; 1.
DR PROSITE; PS50255; CYTOCHROME_B5_2; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|RuleBase:RU362121};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU362121};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU362121};
KW Reference proteome {ECO:0000313|Proteomes:UP000019471};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 38..116
FT /note="Cytochrome b5 heme-binding"
FT /evidence="ECO:0000259|PROSITE:PS50255"
SQ SEQUENCE 127 AA; 14279 MW; CEE1C67C8B68C17C CRC64;
MFSRVGMAKE ETLRSGEELG SATGEYHVVQ NGLPNQDLPA IPANEVRRRN GKSCPDIWIV
IDDIVYDCTI FVNEHPGGDT VIRSFAGKDC SWQFHRVHGF QKNRKWLPGL RVGQTKGVEN
PYPKPKS
//
