ID   W9WD30_9EURO            Unreviewed;       917 AA.
AC   W9WD30;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=Piwi domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=A1O5_11074 {ECO:0000313|EMBL:EXJ65833.1};
OS   Cladophialophora psammophila CBS 110553.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC   Cladophialophora.
OX   NCBI_TaxID=1182543 {ECO:0000313|EMBL:EXJ65833.1, ECO:0000313|Proteomes:UP000019471};
RN   [1] {ECO:0000313|EMBL:EXJ65833.1, ECO:0000313|Proteomes:UP000019471}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 110553 {ECO:0000313|EMBL:EXJ65833.1,
RC   ECO:0000313|Proteomes:UP000019471};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Cladophialophora psammophila CBS 110553.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EXJ65833.1}.
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DR   EMBL; AMGX01000023; EXJ65833.1; -; Genomic_DNA.
DR   RefSeq; XP_007749837.1; XM_007751647.1.
DR   AlphaFoldDB; W9WD30; -.
DR   STRING; 1182543.W9WD30; -.
DR   GeneID; 19195764; -.
DR   eggNOG; KOG1041; Eukaryota.
DR   HOGENOM; CLU_004544_4_1_1; -.
DR   OrthoDB; 3060088at2759; -.
DR   Proteomes; UP000019471; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   CDD; cd02846; PAZ_argonaute_like; 1.
DR   CDD; cd04657; Piwi_ago-like; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 2.170.260.10; paz domain; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR014811; ArgoL1.
DR   InterPro; IPR032472; ArgoL2.
DR   InterPro; IPR032474; Argonaute_N.
DR   InterPro; IPR003100; PAZ_dom.
DR   InterPro; IPR036085; PAZ_dom_sf.
DR   InterPro; IPR003165; Piwi.
DR   InterPro; IPR045246; Piwi_ago-like.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR22891; EUKARYOTIC TRANSLATION INITIATION FACTOR 2C; 1.
DR   PANTHER; PTHR22891:SF188; INTERFERENCE AND GENE SILENCING PROTEIN (QDE2), PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05280)-RELATED; 1.
DR   Pfam; PF08699; ArgoL1; 1.
DR   Pfam; PF16488; ArgoL2; 1.
DR   Pfam; PF16486; ArgoN; 1.
DR   Pfam; PF02171; Piwi; 1.
DR   SMART; SM01163; DUF1785; 1.
DR   SMART; SM00950; Piwi; 1.
DR   SUPFAM; SSF101690; PAZ domain; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50821; PAZ; 1.
DR   PROSITE; PS50822; PIWI; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000019471}.
FT   DOMAIN          344..377
FT                   /note="PAZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50821"
FT   DOMAIN          569..885
FT                   /note="Piwi"
FT                   /evidence="ECO:0000259|PROSITE:PS50822"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   917 AA;  101936 MW;  1760C39B67C77FCB CRC64;
     MLRLSSRKKP LPWPEASQDE ELTALSPHSH SPGAFAHLDV EIEKLEGEIE QHVLRSSRPD
     PSLPIRPGFG TEGRKVLLYA NYMHLDWGSV VLYRYSLSFS TDLATGKSIK AKDQERVVSL
     LLAQNFSQNR SGIVTDFKSL IISNTKLDPS LQGYIITYMM QEGTNTLSEL IAYLTSTRAD
     EVLSSKETII QALNIVIGHN LKATSQITSI RSNQHYPKNP PPSERFDLGV GLTAIRGFFM
     SVRAATGRIL VNVQVKHSPF YNAGPLVRLV EDFGAATDFD RNKLDKFLEG LTVHPSHPAR
     RNKAGQLVPR PKVISGLATK GDGRKRPHRP IIPEFGAGAD RIQFWLDGEK KYVSVLSFFQ
     QTYNITLKYP RMPVLNVPPG QAFKHQLSSD QTKNISPFTI RKPIYNAQSI VREGVAMLNF
     GQSANPTHNA FNLNVKPRLI TVPGRVLGSP NVNYGNKKTV ATRSGSWNML NTQFVSNVHV
     DKWTWLFIKT KSYKGPLSNR QDLEAAVREF ASALCKVGIQ CTNCSPGQEV TVQFGTGKDI
     STVNEEVDKA IHKVSSTFFS TCASAQKQFV LIILASDKPE LYNRVKVNCD VREGINNVCV
     LASTFAKRNP HVFANMALKV NLKLGGVNQS LNPSKLGIAA GGKTMFVGLD VTHPSVGSLD
     VAPSVVGMVS SIDQLLGQWR ASVVIQERRK EMVWGLKDLM KKHLALWRRH NKGLLPDNIV
     VYRDGVSEGQ HQVVLDEEGP LIQAACAEVY PANATKEKLP RLNITIVSKR HHTRFYPTKE
     KEPDGSKNPF NGTVVDRGVT EARGWDFWMQ AHATVQGTAR PIHYFVVYDE ATTPTGIRFT
     NAADALEDLT HNMCYLFGRC TREVSLCPPA YYADLVCDRA RPYLSEVFEP SSEEGSPLIS
     QNMVTTHPRV ANSMFFI
//