ID W9WDR5_9EURO Unreviewed; 963 AA.
AC W9WDR5;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 22-FEB-2023, entry version 30.
DE RecName: Full=ER membrane protein complex subunit 1 {ECO:0000256|ARBA:ARBA00020824};
GN ORFNames=A1O5_10692 {ECO:0000313|EMBL:EXJ66078.1};
OS Cladophialophora psammophila CBS 110553.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=1182543 {ECO:0000313|EMBL:EXJ66078.1, ECO:0000313|Proteomes:UP000019471};
RN [1] {ECO:0000313|EMBL:EXJ66078.1, ECO:0000313|Proteomes:UP000019471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 110553 {ECO:0000313|EMBL:EXJ66078.1,
RC ECO:0000313|Proteomes:UP000019471};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora psammophila CBS 110553.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Component of the ER membrane protein complex (EMC).
CC {ECO:0000256|ARBA:ARBA00011276}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004115}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the EMC1 family.
CC {ECO:0000256|ARBA:ARBA00007904}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ66078.1}.
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DR EMBL; AMGX01000021; EXJ66078.1; -; Genomic_DNA.
DR RefSeq; XP_007749458.1; XM_007751268.1.
DR AlphaFoldDB; W9WDR5; -.
DR STRING; 1182543.W9WDR5; -.
DR GeneID; 19195385; -.
DR eggNOG; KOG2103; Eukaryota.
DR HOGENOM; CLU_005034_0_1_1; -.
DR OrthoDB; 37872at2759; -.
DR Proteomes; UP000019471; Unassembled WGS sequence.
DR GO; GO:0072546; C:EMC complex; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR026895; EMC1.
DR InterPro; IPR011678; EMC1_C.
DR InterPro; IPR002372; PQQ_repeat.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR21573:SF0; ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1; 1.
DR PANTHER; PTHR21573; UNCHARACTERIZED; 1.
DR Pfam; PF07774; EMC1_C; 1.
DR Pfam; PF13360; PQQ_2; 2.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 2.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019471};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..963
FT /note="ER membrane protein complex subunit 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004931214"
FT TRANSMEM 934..952
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 740..961
FT /note="ER membrane protein complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07774"
SQ SEQUENCE 963 AA; 104518 MW; EB5BB6E95F610B07 CRC64;
MRWYGVVSIL LTLFWPTCAI FADDAFHIDF HHALLGSPQP HTTFFHKPHS NTNASLLYTV
SDKAVLGAVN PKDGSVLWRQ PLAGQPIDNA SSSFLVSGER DGQLVSGYDA TVACWDALDG
RLIWDYKLPE GTAIDGLQAI PLQGSVTDGV TQDFMVLATP TDSQTHTSVI RIAGDGSGQR
WQHIDSSTAH GSSVSIAATS KHIYYITVSH GLLTSNKAKV VTLDSATGHE TSQTGVHVDA
EPLGTNRRYA AASCSKFPFL ISAERPFRSV KVSLLNNPKV LSLTLDEKGE EIVDITVHAD
CDQAAATHFL LHIKGKTRQW AEVFHVNTKS GDVTKAYSLP ATEEESIFTV SSYEATAFFI
RSTESEVFLY SSESHGQLGR WKKTNFKTSP GSFRSHATAE VVSRGKASYA VRVAEFSTSG
DWSLIRNGEL QWSRPEMLAY ANIAAWDENG TPDALAEELD LESSVNPWMA YIHRLKRHLH
DLTSLPEYLR SLPDSILKYT PDADAITRQN LVGTKVVIVA TSRKEVIALD ATTPGVLRWQ
SDLSGYIPGD AEMKSVTVAG GKASVYLSNG SLIVLNASNG SLIEYQPGTI PISHLIRIPG
SPPPAVIKVG SDGVPHLAED LVHVTALEGN VVVTISPEGK AVGWTVGRNV EKTWILKPQE
GMKIVHAVAR AEHDPVASIG RVLGDRSVLY KYLSPNIALL LATSHSGALT VYLIDAMTGA
ILHTATHSGV LSSDIPAVIS ENWYAYTFTA RDPFTSGLSN QLIISELYES SVPNDRGLLS
ARTNYSVFSV DGAAAKPHVI SQSYTVAEPI SHLAVSQTAQ GITTRQLLAT LPNSNAIIGI
PREILDPRRP VERDPNATER EEGLTRYMPN LEFDPKYYLT HAREVMGIKD VLSSPSLLES
TSVVFAFGHD VFGTAITPSM AFDVLGKGFN RVQLVLTVVA LFVGVGALRP LVRKKTVEGR
WKQ
//
