ID W9WRV1_9EURO Unreviewed; 982 AA.
AC W9WRV1;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=116 kDa U5 small nuclear ribonucleoprotein component {ECO:0000256|ARBA:ARBA00018774};
DE AltName: Full=Elongation factor 2 {ECO:0000256|ARBA:ARBA00017891};
DE AltName: Full=U5 snRNP-specific protein, 116 kDa {ECO:0000256|ARBA:ARBA00031432};
GN ORFNames=A1O5_09374 {ECO:0000313|EMBL:EXJ67361.1};
OS Cladophialophora psammophila CBS 110553.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=1182543 {ECO:0000313|EMBL:EXJ67361.1, ECO:0000313|Proteomes:UP000019471};
RN [1] {ECO:0000313|EMBL:EXJ67361.1, ECO:0000313|Proteomes:UP000019471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 110553 {ECO:0000313|EMBL:EXJ67361.1,
RC ECO:0000313|Proteomes:UP000019471};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora psammophila CBS 110553.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ67361.1}.
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DR EMBL; AMGX01000016; EXJ67361.1; -; Genomic_DNA.
DR RefSeq; XP_007748143.1; XM_007749953.1.
DR AlphaFoldDB; W9WRV1; -.
DR STRING; 1182543.W9WRV1; -.
DR GeneID; 19194070; -.
DR eggNOG; KOG0468; Eukaryota.
DR HOGENOM; CLU_002794_11_2_1; -.
DR OrthoDB; 166721at2759; -.
DR Proteomes; UP000019471; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR CDD; cd04098; eEF2_C_snRNP; 1.
DR CDD; cd04090; EF2_II_snRNP; 1.
DR CDD; cd01683; EF2_IV_snRNP; 1.
DR CDD; cd16264; snRNP_III; 1.
DR CDD; cd04167; Snu114p; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 3.90.1430.10; Yeast translation eEF2 (G' domain); 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR031950; EFTUD2_N.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR044121; Snu114_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR InterPro; IPR035655; U5-116kDa_C.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF6; 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF16004; EFTUD2; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:EXJ67361.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000019471};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 130..315
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 18..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 982 AA; 108958 MW; BD5FB52BD0305829 CRC64;
MDDLYDEFGN FIGEAVSDEE ASQDGVAGQH YVYDEESEPE EQAPAVQSME VDEEGPSNAV
ILHEDKQYYP TAQQVYGEEV ETLVQEEDAQ PLTQPIIAPV TQKKFQVQEA GLPPVHYSRE
FMTDLLNFPE GIRNIAVAGH LHHGKTAFVD MLVMQTHDLE ERLDKRIGRR RDEQLRYTDT
HFLERERGIS IKAAPISLVM QGTKGKSHIL NIIDTPGHVN FVDEVASALR LVDGVVLVVD
VVEGVQINAE QVIKHAVLED IPMVLVINKM DRLILELKIP PTDAYFKLKH VVEEVNTVIE
NTIPGRGEKR RLSPEKGNVA FACTSMDWVF TLPSFAKMYA ETYPKVDAAE FSKRLWGDIF
FNPRSRKFTR KGTEEGSKRA FVNFVLEPIY KLFSHTISES PEDLAPTLQT LGISLKPSQL
KSDAKVLLKL VCAQFFGTAS GFVDMVVQHI PSPVEGASRM LDNYYTGTAG SKVSEAMSKC
DSDGPLVVEV TKLFSSSDAK TFNAFGRVMS GTASPDQVVR VLGEAYSLED EEDSTTATIM
AVQIACSRYN IPVSGVPAGN LVLLSGIDNS IVKTATVVAE KYPDNEDAYI FKAIRHFTES
VFKVAVEPVN PSELPKMLEG LRKINKSYPL ITTKVEESGE HVVLGTGELY MDCVLHDLRT
QYAEMDIKVS DPVTRFCETV TETSAIMCYA LTPNKKNKLT MIAEPLDDGI AEDIEAGVVK
IRDPIRKVAK FFEEKYEWDK LAARSIWAFG PDEMGPNILC DDTLPSTTDK KLLKSVQESI
KQGFSWGTRE GPLCEEPIRN TKFRVTGAEL ATEPIFRGGG QIIPTARRAV YSSFLMASPR
LMEPIYSVHM TGPADSISGL YTVLMKRRGH VVSDGPVAGT PLYAAKALLP VIDSFGFETD
LRIHSQGAAS VSLVFERWDV VPGDPLDKSI RVRPLEMAAP QQAARDFVLK TRRRKGLSED
VDVKRFLEPE LLAGLRESGV LD
//
