ID W9WTP3_9EURO Unreviewed; 565 AA.
AC W9WTP3;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Dioxygenase {ECO:0008006|Google:ProtNLM};
GN ORFNames=A1O5_08167 {ECO:0000313|EMBL:EXJ68375.1};
OS Cladophialophora psammophila CBS 110553.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=1182543 {ECO:0000313|EMBL:EXJ68375.1, ECO:0000313|Proteomes:UP000019471};
RN [1] {ECO:0000313|EMBL:EXJ68375.1, ECO:0000313|Proteomes:UP000019471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 110553 {ECO:0000313|EMBL:EXJ68375.1,
RC ECO:0000313|Proteomes:UP000019471};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora psammophila CBS 110553.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|PIRSR:PIRSR604294-1};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604294-1};
CC -!- SIMILARITY: Belongs to the carotenoid oxygenase family.
CC {ECO:0000256|ARBA:ARBA00006787}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ68375.1}.
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DR EMBL; AMGX01000013; EXJ68375.1; -; Genomic_DNA.
DR RefSeq; XP_007746941.1; XM_007748751.1.
DR AlphaFoldDB; W9WTP3; -.
DR STRING; 1182543.W9WTP3; -.
DR GeneID; 19192868; -.
DR eggNOG; KOG1285; Eukaryota.
DR HOGENOM; CLU_016472_5_0_1; -.
DR OrthoDB; 294919at2759; -.
DR Proteomes; UP000019471; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR InterPro; IPR004294; Carotenoid_Oase.
DR PANTHER; PTHR10543; BETA-CAROTENE DIOXYGENASE; 1.
DR PANTHER; PTHR10543:SF24; CAROTENOID ISOMEROOXYGENASE; 1.
DR Pfam; PF03055; RPE65; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR604294-1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR604294-1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019471}.
FT REGION 396..424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 223
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 272
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 345
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 547
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
SQ SEQUENCE 565 AA; 62892 MW; E0A2285CF3C3AAEE CRC64;
MGNPGAKPTT TVHYHDWPNT LGFDAKYEEK TPVELRVEGI IPAYTAGTLF RTGLGPRSIH
TSKDTEFKVN HWFDNFSQVH RFQIHTSQPD SKVRVTYNSR LVSDGLIEKI QKTGKLDEFT
FAAKYDPCKS FFQKVQAVFQ PSAPRAKPNE VNAAVTMSVN FPGFTRDGHR ANGPRDPSQA
MTLCNKTDAN VFQFLEPETL EPVGVAHQTI LHPDLKGVGS GAHAKSDPAT GDVFNYNLDF
GRTGTYRLWR ASASTGKTSI LATFHHTPAY LHSLLLTKNY VILCVWNSFY KAGGASILWN
RNLLDAMGWD DKRPTTWFVV DKRSPEEGGK GVVAKYTSDA FYSFHTINAY EEPSRTHQGA
VDIVCDLAAY ENMDVLHHFY LDNLMSHLPQ ARAYADSLSP SSRPNYRRYR LPGIPSTPKP
EQEKASLEYE STKADAFELP IINPKMVTRK HRYMYGITDT GKSTFVDGLV KYDAETHATV
RWSVHGQSPG EPIFVADPRS EDEDGGVLLS VVLDGPGGKS YLLVLDAKTM TEIGRAHVDG
VIGFGFHGLH VSSREPVGRF NGMHL
//
