ID W9X335_9EURO Unreviewed; 570 AA.
AC W9X335;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=4-coumarate-CoA ligase {ECO:0000313|EMBL:EXJ74867.1};
GN ORFNames=A1O5_01563 {ECO:0000313|EMBL:EXJ74867.1};
OS Cladophialophora psammophila CBS 110553.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=1182543 {ECO:0000313|EMBL:EXJ74867.1, ECO:0000313|Proteomes:UP000019471};
RN [1] {ECO:0000313|EMBL:EXJ74867.1, ECO:0000313|Proteomes:UP000019471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 110553 {ECO:0000313|EMBL:EXJ74867.1,
RC ECO:0000313|Proteomes:UP000019471};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora psammophila CBS 110553.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ74867.1}.
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DR EMBL; AMGX01000002; EXJ74867.1; -; Genomic_DNA.
DR RefSeq; XP_007740369.1; XM_007742179.1.
DR AlphaFoldDB; W9X335; -.
DR STRING; 1182543.W9X335; -.
DR GeneID; 19186296; -.
DR eggNOG; KOG1176; Eukaryota.
DR HOGENOM; CLU_000022_59_2_1; -.
DR OrthoDB; 1404660at2759; -.
DR Proteomes; UP000019471; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd05911; Firefly_Luc_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR24096:SF149; 4-COUMARATE--COA LIGASE 1-RELATED; 1.
DR PANTHER; PTHR24096; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:EXJ74867.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019471};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 73..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 26..422
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 475..551
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 570 AA; 63601 MW; FE335BACF520EE8E CRC64;
MPYRSRWSIP LPQCSFPTFL FGSPHKDPGD KKAYVDSRRP EELFLTRKAF RLWSQRVALG
LLKSTNFQPG DRILVFSGNT LATPVAFMGI VMAGGVFTGA NPTFTPRELA YQLRDSDATY
LFCSDASIDT GIEAAKQAGL DKSRVYVYNE SVFLCDKASQ RGLKGCRSWS ELIAPAEEAQ
DFQWDELDGD KCHKTIALNY SSGTTGVPKG VEVTHYNYIA NTLQYNHLPT LAPNYVEMND
RSRWLCFLPL YHAMAQTIYI AGALLRGIPV YIMPKFDFVE MLGNIERFRI TDLTIVPPIA
VALTKHLAAK TADLSSIETM NCGSAPLGSD ICRAIEKLCG GNFNMKQGWG MTEVTCSLLG
WDPNKISTSF GVGEPNANCE AKIVKVMTDF RGNESFSEVT ERGAEHTGEL WCRGPNVMKG
YWRNPTATKN AFSPDAERWL RTGDIAYVDD EGCFYIVDRI KELIKVKANQ VAPAELESLI
LEHPAVADVA VIGVPTTDGD ERPRAFVLRQ PHIQVSEQEI FDYVKERTVA YKWLTAGVQW
VDAIPKNPSG KILRRQLREA SKIQSVQARL
//
