ID W9X6R0_9EURO Unreviewed; 561 AA.
AC W9X6R0;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 08-NOV-2023, entry version 31.
DE RecName: Full=Cystathionine gamma-synthase {ECO:0008006|Google:ProtNLM};
GN ORFNames=A1O5_03757 {ECO:0000313|EMBL:EXJ72611.1};
OS Cladophialophora psammophila CBS 110553.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=1182543 {ECO:0000313|EMBL:EXJ72611.1, ECO:0000313|Proteomes:UP000019471};
RN [1] {ECO:0000313|EMBL:EXJ72611.1, ECO:0000313|Proteomes:UP000019471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 110553 {ECO:0000313|EMBL:EXJ72611.1,
RC ECO:0000313|Proteomes:UP000019471};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora psammophila CBS 110553.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|RuleBase:RU362118}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ72611.1}.
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DR EMBL; AMGX01000005; EXJ72611.1; -; Genomic_DNA.
DR RefSeq; XP_007742558.1; XM_007744368.1.
DR AlphaFoldDB; W9X6R0; -.
DR STRING; 1182543.W9X6R0; -.
DR GeneID; 19188485; -.
DR eggNOG; KOG0053; Eukaryota.
DR HOGENOM; CLU_011302_3_0_1; -.
DR OrthoDB; 35837at2759; -.
DR Proteomes; UP000019471; Unassembled WGS sequence.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR42699; -; 1.
DR PANTHER; PTHR42699:SF1; CYSTATHIONINE GAMMA-SYNTHASE-RELATED; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|RuleBase:RU362118};
KW Reference proteome {ECO:0000313|Proteomes:UP000019471}.
SQ SEQUENCE 561 AA; 62340 MW; DFD12719FC5C9234 CRC64;
MALEIQTPFG TALPPAPRHA ITVHLPEWRS IVRFKDHDPE LLTALKSMYP RFILHKDVLA
LTQKIIEVAG VEEGQGQQGC FVFPSWRAAR DCKDFATSPR RGPGKTVPRD RVSIRIFKTH
GHVPLLYAVM FPVESTPTVH GFWVNAGVGI SSRLAEDCLR HIGSLREVKH DDEEEEERGS
PDGLAHRQIK ERIAGLLNRA PTDPHRTARV SPNDVYFFST GMASIYWVHR YLLTKYSAPS
VLFGFSFHST IHVLEDFGPG VDFLGLGSVQ DLEALEKHLL LASQRERERG KRGGGVQAIW
AEFPSNPLLS TPDLRRLREL ADAHGALVVV DDTVGSFCNV DVLDVADIVV TSLTKSFSGY
ADVMAGSAVL SPLSSRYAEL KALFETEHRD NLYTRDAETL ERNSRDYLAR SAVLNNNAER
LVEYLHSEAL NPTSGVKQVF YPTVNADTLA NYTAYMRSTT PEFPRPGYGC LLSVEFRDVE
TATAFYDHLH VHKGPHLGAH LTLALPYALG VYGNEADWAS EYNVRQAQVR ISVGLEETGN
LVDTFRRAIE AADGRSAGLQ N
//
