ID   W9XA64_9EURO            Unreviewed;       345 AA.
AC   W9XA64;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=NAD-dependent epimerase/dehydratase domain-containing protein {ECO:0000259|Pfam:PF01370};
GN   ORFNames=A1O5_09332 {ECO:0000313|EMBL:EXJ67319.1};
OS   Cladophialophora psammophila CBS 110553.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC   Cladophialophora.
OX   NCBI_TaxID=1182543 {ECO:0000313|EMBL:EXJ67319.1, ECO:0000313|Proteomes:UP000019471};
RN   [1] {ECO:0000313|EMBL:EXJ67319.1, ECO:0000313|Proteomes:UP000019471}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 110553 {ECO:0000313|EMBL:EXJ67319.1,
RC   ECO:0000313|Proteomes:UP000019471};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Cladophialophora psammophila CBS 110553.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. Dihydroflavonol-4-reductase subfamily.
CC       {ECO:0000256|ARBA:ARBA00023445}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EXJ67319.1}.
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DR   EMBL; AMGX01000016; EXJ67319.1; -; Genomic_DNA.
DR   RefSeq; XP_007748101.1; XM_007749911.1.
DR   AlphaFoldDB; W9XA64; -.
DR   STRING; 1182543.W9XA64; -.
DR   GeneID; 19194028; -.
DR   eggNOG; KOG1502; Eukaryota.
DR   HOGENOM; CLU_007383_9_2_1; -.
DR   OrthoDB; 552946at2759; -.
DR   Proteomes; UP000019471; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR10366:SF562; ALDEHYDE REDUCTASE II (AFU_ORTHOLOGUE AFUA_1G11360); 1.
DR   PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019471}.
FT   DOMAIN          15..196
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
SQ   SEQUENCE   345 AA;  38043 MW;  BA8404AFD48DE0DB CRC64;
     MSSMTERAIP AGSLVVVSGA NGFIASHVVD QLLLAGYRVR GTVRDAKKSA WLIEYFGAKY
     GPGKFELIEV PEMAADGAFD EAVKGASGFI HTATPVMVSY DPNEGIPIVV NGTVNALRAA
     ASEPSIKRFV LTSSSTAAIS PKPNIEFSAD ESTWNDEAVK AAWAPPPYEG EQRKLDVYSA
     SKTQGEQAAW KFMKEEKPGF VLNTVLPNCN MGLVLSPEHQ GAPSTVGWLK ALWNEFKGQE
     KLKFNPPQYY VNVQDTARVH VGALIFMDVQ EERLYDFAYP FNWNDILAIY RKLYPEHKFM
     DDIPDLGRDL SKVTNERAEE IVKRFGRPGW ASLEDSVADA AKGWA
//