ID W9XCT0_9EURO Unreviewed; 554 AA.
AC W9XCT0;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=CDF family cation efflux system protein {ECO:0000313|EMBL:EXJ78297.1};
GN ORFNames=A1O3_09458 {ECO:0000313|EMBL:EXJ78297.1};
OS Capronia epimyces CBS 606.96.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Capronia.
OX NCBI_TaxID=1182542 {ECO:0000313|EMBL:EXJ78297.1, ECO:0000313|Proteomes:UP000019478};
RN [1] {ECO:0000313|EMBL:EXJ78297.1, ECO:0000313|Proteomes:UP000019478}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 606.96 {ECO:0000313|EMBL:EXJ78297.1,
RC ECO:0000313|Proteomes:UP000019478};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capronia epimyces CBS 606.96.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the cation diffusion facilitator (CDF)
CC transporter (TC 2.A.4) family. SLC30A subfamily.
CC {ECO:0000256|ARBA:ARBA00008873}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ78297.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMGY01000009; EXJ78297.1; -; Genomic_DNA.
DR RefSeq; XP_007737742.1; XM_007739552.1.
DR AlphaFoldDB; W9XCT0; -.
DR STRING; 1182542.W9XCT0; -.
DR GeneID; 19173542; -.
DR eggNOG; KOG1483; Eukaryota.
DR HOGENOM; CLU_013430_4_2_1; -.
DR OrthoDB; 5482779at2759; -.
DR Proteomes; UP000019478; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0098771; P:inorganic ion homeostasis; IEA:UniProt.
DR GO; GO:0030003; P:intracellular monoatomic cation homeostasis; IEA:UniProt.
DR Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 2.
DR InterPro; IPR002524; Cation_efflux.
DR InterPro; IPR036837; Cation_efflux_CTD_sf.
DR InterPro; IPR027469; Cation_efflux_TMD_sf.
DR NCBIfam; TIGR01297; CDF; 2.
DR PANTHER; PTHR45820; FI23527P1; 1.
DR PANTHER; PTHR45820:SF4; FI23527P1; 1.
DR Pfam; PF01545; Cation_efflux; 2.
DR SUPFAM; SSF160240; Cation efflux protein cytoplasmic domain-like; 1.
DR SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019478};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 9..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 211..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 264..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 497..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 317..334
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 554 AA; 59477 MW; C98213C14B8C8DC0 CRC64;
MGLSKTQRII VLLVIDSAFF LVELIVGYAV HSLALVADSF HMLNDVLSLC VGLWAVRVAN
TGSSKMYTYG WQRAETLGAL VNGVFLVALC LSIFLEAIQR FVEPQVVTNP KLVLIVGCLG
LASNILGLFL FHDHSHAHGA EDSPHDGDPI RVAEEGHTHT HDEETTAVAD ETGPVEDVLP
QVRVAGYQGS ERKGFTTSDE DNTTISAISS HLPHGRSFAN GGEVHSRHRR RTSGSLVRGF
GSVDNLHIHP ASFRQDIIQA ARLEEQSESS SAEEEALLDE DSPNERSRIF ADNNASSAKG
YGGVGKRVSQ DYSHSAHNHT QPKDGSAKGH GHGHGHDLNM RGVFLHVLGD ALGNIGVIAS
ALIIWQATFP ARYYFDPGIS LVITVIILYS AIPLCKAASR ILLQAVPVGI SIDEITQDIE
ALPHVIEAHH LHVWQLSDTK LVASLHVKVD CVAHGVGSAS YMHLAREIRK CLHAYGIHSS
TIQPEFYTDR IDSPGGSTAI TSGSATGQLS PKAVGSRSAS VRSHETGCLL DCGDKCAGNK
LCCPTDASGR SQKP
//
