ID W9XI10_9EURO Unreviewed; 536 AA.
AC W9XI10;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Amidase domain-containing protein {ECO:0000259|Pfam:PF01425};
GN ORFNames=A1O1_08304 {ECO:0000313|EMBL:EXJ80162.1};
OS Capronia coronata CBS 617.96.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Capronia.
OX NCBI_TaxID=1182541 {ECO:0000313|EMBL:EXJ80162.1, ECO:0000313|Proteomes:UP000019484};
RN [1] {ECO:0000313|EMBL:EXJ80162.1, ECO:0000313|Proteomes:UP000019484}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 617.96 {ECO:0000313|EMBL:EXJ80162.1,
RC ECO:0000313|Proteomes:UP000019484};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capronia coronata CBS 617.96.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ80162.1}.
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DR EMBL; AMWN01000008; EXJ80162.1; -; Genomic_DNA.
DR RefSeq; XP_007727356.1; XM_007729166.1.
DR AlphaFoldDB; W9XI10; -.
DR STRING; 1182541.W9XI10; -.
DR GeneID; 19163155; -.
DR eggNOG; KOG1212; Eukaryota.
DR HOGENOM; CLU_009600_9_2_1; -.
DR OrthoDB; 731186at2759; -.
DR Proteomes; UP000019484; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1300.10; Amidase signature (AS) domain; 1.
DR InterPro; IPR023631; Amidase_dom.
DR InterPro; IPR036928; AS_sf.
DR PANTHER; PTHR46072:SF2; AMIDASE (EUROFUNG); 1.
DR PANTHER; PTHR46072; AMIDASE-RELATED-RELATED; 1.
DR Pfam; PF01425; Amidase; 1.
DR PIRSF; PIRSF001221; Amidase_fungi; 1.
DR SUPFAM; SSF75304; Amidase signature (AS) enzymes; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000019484}.
FT DOMAIN 81..524
FT /note="Amidase"
FT /evidence="ECO:0000259|Pfam:PF01425"
FT ACT_SITE 124
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-1"
FT ACT_SITE 199
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-1"
FT ACT_SITE 223
FT /note="Acyl-ester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-1"
FT BINDING 173
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-2"
FT BINDING 199
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-2"
FT BINDING 220..223
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-2"
SQ SEQUENCE 536 AA; 59427 MW; 564B7597A9BEF39C CRC64;
MSSGSWQDVV RQKRDTRTRL IEPFLGHSDG ATDASILGID NVAELTRLYE DGKLRARDVL
EAYIKRLAIG AGTCQTPADT VSQTNCLTEV FFEETLREAD KLDDYFQQHG KLIGPLHGVP
ITLKDQFDVK GADSTIGYVS RAFQPASEDA AIVRILKDLG AVVLAKTNLP QSIMWCETEN
PLWGLTVNPR DPSFTPGGST GGEAALLALQ GSMIGWGTDI GGSIRIPSHI NGLWGLKPTS
SRLPYQGVPV STEGQEHVPS SVGPLARSLS SLVTIMQTVI QSKPWVLDPK VVPIPWRQDM
YEEIQSRPMR IGILVDDGVV KVHPPIERVL KELEAKLKSA GHEVVSWDCS GHRECIEIMD
LFYTADGGED IRREVQAGGE PFIPHVEALV NRGQAISVYE YWQLNKRKLA AQKAYNDKWN
STKSPATGEP LDVILMPTMP HVAVPHRTCR WVGYTKVWNF LDYTALSFPA GQVQAEVDTV
LEDQYEPRND HDAWNWKLYD PKTMDGHPVG LQIVGRRFEE EKVLGAAAVI ENYIKA
//
