ID W9XM06_9EURO Unreviewed; 1007 AA.
AC W9XM06;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Probable E3 ubiquitin ligase complex SCF subunit sconB {ECO:0000256|ARBA:ARBA00015819};
DE AltName: Full=Sulfur controller B {ECO:0000256|ARBA:ARBA00032113};
DE AltName: Full=Sulfur metabolite repression control protein B {ECO:0000256|ARBA:ARBA00030034};
GN ORFNames=A1O1_07631 {ECO:0000313|EMBL:EXJ81567.1};
OS Capronia coronata CBS 617.96.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Capronia.
OX NCBI_TaxID=1182541 {ECO:0000313|EMBL:EXJ81567.1, ECO:0000313|Proteomes:UP000019484};
RN [1] {ECO:0000313|EMBL:EXJ81567.1, ECO:0000313|Proteomes:UP000019484}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 617.96 {ECO:0000313|EMBL:EXJ81567.1,
RC ECO:0000313|Proteomes:UP000019484};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capronia coronata CBS 617.96.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the SCF(sconB) E3 ubiquitin ligase complex
CC involved in the regulation of sulfur metabolite repression, probably by
CC mediating the inactivation or degradation of the metR transcription
CC factor. {ECO:0000256|ARBA:ARBA00002730}.
CC -!- PATHWAY: Protein modification. {ECO:0000256|ARBA:ARBA00043952}.
CC -!- SUBUNIT: Component of the SCF(sconB) E3 ubiquitin ligase complex.
CC {ECO:0000256|ARBA:ARBA00011725}.
CC -!- SIMILARITY: Belongs to the WD repeat MET30/SCONB/SCON-2 family.
CC {ECO:0000256|ARBA:ARBA00007968}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ81567.1}.
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DR EMBL; AMWN01000007; EXJ81567.1; -; Genomic_DNA.
DR RefSeq; XP_007726688.1; XM_007728498.1.
DR AlphaFoldDB; W9XM06; -.
DR STRING; 1182541.W9XM06; -.
DR GeneID; 19162487; -.
DR eggNOG; KOG0274; Eukaryota.
DR HOGENOM; CLU_000288_103_3_1; -.
DR OrthoDB; 587035at2759; -.
DR Proteomes; UP000019484; Unassembled WGS sequence.
DR CDD; cd22147; F-box_SpPof1-like; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19849; PHOSPHOLIPASE A-2-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR19849:SF3; PROTEIN WITH WD-40 REPEAT DOMAIN; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00320; WD40; 8.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50181; FBOX; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000019484};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 399..446
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT REPEAT 653..692
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 723..742
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 769..808
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 809..850
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 851..890
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 891..929
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 71..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 140..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 478..542
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..97
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 169..190
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..236
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..509
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1007 AA; 111391 MW; 574E9753CE935AB2 CRC64;
MRPPRRMQDL DPKHYPLATT PTPAHLRQIF FEIEGKQTVF REAKDTTLAL EQMEVEQRTL
RNANGTIRTV ETFRPWTETP GDVSTPTYPQ TRGQKRPASP ESIADDEEHT SSPTLPPVSS
ISAQSIDLSV RAGTGLPRLR IHDVQGSHPV TPDSLTRPPR ASRRRVPLST INACRSTNTL
LPSPSVDYRT SLPTPRPPRP GDEQPPILDD DSNSSTDRTV VAPIQRRGSS QDSAVPTPPV
DEEAGPSQPR PPSRRALSSV PSRLHVAGSP SAHDGSLPSP SLSPVTAAAT LQNSGYFADV
DATSEMASQH QIGSRGSTAE VRPSNPFRPL QVLDVDSRLS SRPSAPFMSG SVTDLPAMLD
YFEAIPDELK SYVMHQLLRR CPKPTLQVVA DAVNPALKCD FLTILPPELA LNILKYLDFK
SLCKAAQVSK KWRQMINSDE RAWKELFEAD GYTLAKGELQ KAISEGWGWQ DPVGPHGYEE
NLIYTNNPKP ESEANNSPSP STPPCQNRFS GILRRSKRKA ATMLSGRNKQ VKRKDSSRDC
SNDVMSADWM QRMSSAEGPY NAANAAMLAV PQPNVGLPSL KGLHLYKSLY RRHHLIRRNW
MFEDTKPQHL AFRAHDTHVV TCLQFDSDKI LTGSDDNNIN VYETRTGILR AVLTGHEGGV
WALQYEGNTL VSGSTDRSVR VWNIQEARET QVFRGHTSTV RCLQIVMPVK VGENAEGKPI
MMPKQPLIIT GSRDSTLRVW KLPRPGDAEF IQAENDNDTD SCPYFVRTLT GHQHSVRAIA
AHADTLVSGS YDCTVRVWKI STGETVHRLQ GHTQKVYSVV LDHARNRCIS GSMDNMVRIW
DLNTGSLKYT LEGHTSLVGL LDLNCDKLVS AAADSTLRIW DPENGQCKAT LSAHTGAITC
FKHDGEKVIS GSDRTLKLWN IRTGECIKDL LSDLSGVWQV KFDERRCVAA VQRDGLTYIE
VLDYGAARDG IPEHNLGRRI VVDTDGFEAD ANNDDGDLLE LDGRADM
//
