ID   W9XR30_9EURO            Unreviewed;       859 AA.
AC   W9XR30;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   RecName: Full=DNA polymerase epsilon subunit B {ECO:0000256|ARBA:ARBA00016011};
DE   AltName: Full=DNA polymerase II subunit 2 {ECO:0000256|ARBA:ARBA00032930};
GN   ORFNames=A1O3_06502 {ECO:0000313|EMBL:EXJ82688.1};
OS   Capronia epimyces CBS 606.96.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Capronia.
OX   NCBI_TaxID=1182542 {ECO:0000313|EMBL:EXJ82688.1, ECO:0000313|Proteomes:UP000019478};
RN   [1] {ECO:0000313|EMBL:EXJ82688.1, ECO:0000313|Proteomes:UP000019478}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 606.96 {ECO:0000313|EMBL:EXJ82688.1,
RC   ECO:0000313|Proteomes:UP000019478};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Capronia epimyces CBS 606.96.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase epsilon subunit B family.
CC       {ECO:0000256|ARBA:ARBA00009560}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EXJ82688.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AMGY01000005; EXJ82688.1; -; Genomic_DNA.
DR   RefSeq; XP_007734811.1; XM_007736621.1.
DR   AlphaFoldDB; W9XR30; -.
DR   STRING; 1182542.W9XR30; -.
DR   GeneID; 19170611; -.
DR   eggNOG; KOG3818; Eukaryota.
DR   HOGENOM; CLU_010628_1_0_1; -.
DR   OrthoDB; 166885at2759; -.
DR   Proteomes; UP000019478; Unassembled WGS sequence.
DR   GO; GO:0008622; C:epsilon DNA polymerase complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR   InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR   InterPro; IPR016266; POLE2.
DR   PANTHER; PTHR12708:SF0; DNA POLYMERASE EPSILON SUBUNIT 2; 1.
DR   PANTHER; PTHR12708; DNA POLYMERASE EPSILON SUBUNIT B; 1.
DR   Pfam; PF04042; DNA_pol_E_B; 1.
PE   3: Inferred from homology;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019478}.
FT   DOMAIN          496..808
FT                   /note="DNA polymerase alpha/delta/epsilon subunit B"
FT                   /evidence="ECO:0000259|Pfam:PF04042"
FT   REGION          168..191
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          680..707
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        168..188
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   859 AA;  92260 MW;  5CA023C5810144D1 CRC64;
     MEEPVSTPRL PPPSFTASSA FTKEQLLSSS PGFGTPAYPI VNRPPGIKQP FAAKPNKAPD
     NVPTVLPILL PPQTLRPVAF RTLTKKHNLT LTSSGLGVLS TFVGKFCGSG WREEGLAERV
     LDEVAKLWKR NGGGLIVEDG PDKKLSNIFK ILEPYMCGGR LDMAKLSRSN SGMSSPNLSR
     TVSFSDRPGL NRDDSLASLG VSDLHIEGKG DQDEEEDHET QLDPRSYLKV VSSFDQPRLV
     YSTSKKCFEP VAGPPSLLPA IQHKVSMFRN RYHLVHQRLM RNESFQAPTF STIARPPSLM
     HSGSSVATLQ QAYKITPISN LLGRSGTPHL LLGMLVHSAA GDLALSDLSG SVVLDLSVAR
     PVPEDGAWFC PGMIVLVEGT YEEDGSHNSN LGSASGVGGQ IKGHFNVDTM AGPPAERRAT
     TIGTSNGPES DNNSHTSVGA GFGWIDFLGV GSEKGIGSQM RRIQNRIFGA PPTSLYDISD
     TSGSIDEEVQ PLRTKIAILG ECTLDSPRTL EAIRAILSSY SASSSEIVDL PLSIVMMGNF
     ASAACMAGST KGGGSVEYKE NFDALASVLS EFPSLLSSTT LVFVPGDNDP WASAFSAGAA
     GVLPRPGVPE IFTSRIRRAI ANANLEKGRK DKNSPAGEAV WATNPARMSL FGPLEDIVLF
     RDDITSRFRR NAITFSKLDG DDDEDMVEDG SNNAGIGSEQ PAPAIDTEDE RLDVASDMDM
     DKDGLDRRVH EATSHLPSAV SVPTTATSKP NGYTLHAARK LIKTVLDQSH LAPFAHSIRP
     VFWDHASSLS LYPLPTALVL ADSETPTFAI TYEGCLVMNP GRVVDEMAMS RAAARGAGVG
     RWIEYDVKTR KGESREVRF
//