ID W9YRM9_9EURO Unreviewed; 635 AA.
AC W9YRM9;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Sorting nexin-41 {ECO:0000313|EMBL:EXJ95223.1};
GN ORFNames=A1O1_00343 {ECO:0000313|EMBL:EXJ95223.1};
OS Capronia coronata CBS 617.96.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Capronia.
OX NCBI_TaxID=1182541 {ECO:0000313|EMBL:EXJ95223.1, ECO:0000313|Proteomes:UP000019484};
RN [1] {ECO:0000313|EMBL:EXJ95223.1, ECO:0000313|Proteomes:UP000019484}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 617.96 {ECO:0000313|EMBL:EXJ95223.1,
RC ECO:0000313|Proteomes:UP000019484};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capronia coronata CBS 617.96.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004481}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ95223.1}.
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DR EMBL; AMWN01000001; EXJ95223.1; -; Genomic_DNA.
DR RefSeq; XP_007719452.1; XM_007721262.1.
DR AlphaFoldDB; W9YRM9; -.
DR STRING; 1182541.W9YRM9; -.
DR GeneID; 19155251; -.
DR eggNOG; KOG2273; Eukaryota.
DR HOGENOM; CLU_014456_0_0_1; -.
DR OrthoDB; 5475877at2759; -.
DR Proteomes; UP000019484; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR CDD; cd06867; PX_SNX41_42; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 2.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR044106; PX_Snx41/Atg20.
DR PANTHER; PTHR46979; SORTING NEXIN-41; 1.
DR PANTHER; PTHR46979:SF2; SORTING NEXIN-41; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000019484}.
FT DOMAIN 87..207
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 248..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 446..528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 557..584
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 13..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..278
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..467
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 470..488
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 503..517
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 635 AA; 70342 MW; 2840317E90E21C8C CRC64;
MWQDDEDNNP YGSFDNHDSS TVPTNPALSA SYSNSSSPPS SHSSPDEPPQ FLSRPDNLSD
EDEDYNANPE SAPTPPKGGY DSRVQQILFE NPDLEIVITD AGKSSDGGYI VYKIRTGDIE
VTRRYSEFSS LRAALVNLHP TLVIPPIPEK HTMADYAAKP TKAKEDVGII DLRKRMLGVF
LNRCRRMKDV VEDGVWWRFL DPNSSWNEVL HAYPISSIPK NNLKAPPLDP ANPTPAHNWL
PVPSVSAKLK SAGPTSSSGT PISPPEQTYP SAASHTTPGP QVFGRFPPTT DKLSETDLDP
YFINFEASTR ELELLLQGSI EKVNRRTLEH LTKLSADLAE LGARYNGFSL SEQSPTVAAA
IERVGQAVDS TYISTEELAL GLGATFAEPM RESAQFAGVV RNVLRYRVLK RVQQDMTRDD
LDKKRNLLEA LERSEAEAKR IDAYLSGSTT LSSPPRRSTS NASARTASER HAGPGREGHD
ETESVDSDFP PTHGETPSSP PSAAQGEPNP PTGPTSPTSH RKSPSGNFVT NKIFGSFRHA
VNGFVDVDPE RTRRDQIGKT RESLTQLEQA LEVSEKDVKD ATQGVMRDLK RFQKEKEDDF
QRYMIAYARC HIEWARKNLE TWSEAREEVD KIVAR
//
