ID   W9Z307_9EURO            Unreviewed;       815 AA.
AC   W9Z307;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=PNPLA domain-containing protein {ECO:0000259|PROSITE:PS51635};
GN   ORFNames=A1O1_01456 {ECO:0000313|EMBL:EXJ96330.1};
OS   Capronia coronata CBS 617.96.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Capronia.
OX   NCBI_TaxID=1182541 {ECO:0000313|EMBL:EXJ96330.1, ECO:0000313|Proteomes:UP000019484};
RN   [1] {ECO:0000313|EMBL:EXJ96330.1, ECO:0000313|Proteomes:UP000019484}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 617.96 {ECO:0000313|EMBL:EXJ96330.1,
RC   ECO:0000313|Proteomes:UP000019484};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Capronia coronata CBS 617.96.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EXJ96330.1}.
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DR   EMBL; AMWN01000001; EXJ96330.1; -; Genomic_DNA.
DR   RefSeq; XP_007720559.1; XM_007722369.1.
DR   AlphaFoldDB; W9Z307; -.
DR   STRING; 1182541.W9Z307; -.
DR   GeneID; 19156358; -.
DR   eggNOG; KOG4231; Eukaryota.
DR   HOGENOM; CLU_000288_125_6_1; -.
DR   OrthoDB; 614488at2759; -.
DR   Proteomes; UP000019484; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0046486; P:glycerolipid metabolic process; IEA:UniProt.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd07216; Pat17_PNPLA8_PNPLA9_like3; 1.
DR   Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR002641; PNPLA_dom.
DR   PANTHER; PTHR24185; CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA; 1.
DR   PANTHER; PTHR24185:SF4; SERINE HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G07870)-RELATED; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF01734; Patatin; 1.
DR   SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51635; PNPLA; 1.
PE   4: Predicted;
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019484}.
FT   DOMAIN          26..227
FT                   /note="PNPLA"
FT                   /evidence="ECO:0000259|PROSITE:PS51635"
SQ   SEQUENCE   815 AA;  89765 MW;  9529EF6B760DE141 CRC64;
     MAQAVSVDRA TGGPSNPVDS TGLCLLSLDG GGVRGLSTLH ILKSIMTRLN HERRESGASE
     LKPCELFDLI GGTSTGGLIA IMLGRLEMDV DECITAYNRL IKAVFEQKAH WTPLSWRGQV
     QPRFDSAKLK AVIDEVITSR GYSPTEPFNN GKSHGCHVFV CTAAKDLYGI TRLRSYDLPE
     KPSVPATISE AALATSAATG FFDPVFIGAR QFVDGALGVN NPVEEVEGEA SDIWCADTGD
     VKSLVKCFIS IGTGNPGKKA IEHNLLKFLS QTLVQITTET EETAKRFVGR WRQHFVQNRY
     FRLNVEQGLQ DVDLAEYKEQ GRIEEAAHQY LDDQQQIFRV RDCVANLKQK QKARTVNVHW
     SVRRPVHTLF TGRDCILASL EDKIQKALVE VTPTVQCRIV ISGMGGQGKS EICLQLAQRL
     RTLFWGVFWV DVSTSSLAEN GFLDIATRLQ ISASTWEDGR QALANVQQPW MLVLDNADDL
     DVDYQTYFPP GSAGVMVLTS RNEECQQYAT ADFVALEGLT TEEATALLLK VAGVAPGAAG
     EQHSVRNDDA RRVATLLQSH PLALIQAGAY VKRGHCGLAE YPRVYERQRK RLLRFRPSQV
     QSRYRDVYAT FEASVEILQA SPTESSHDAL ELLPLLAVGG PSPLPLSLFA AAWTGAHGIR
     EGEPGDEDDL RLTTWHVSCL PSWITVGADA WDSFRLVEAV SALRALALVS RHVEDGQVRV
     SMHPLVHAWA RDRQDERRQH ASWVAMSCVV ALSGGDDMWR VQARLLQPHV QATTSWEMGC
     MFGSAPRAAV AGILVACRLL IDGGWICMTS WVGTY
//