ID W9ZDJ2_9EURO Unreviewed; 1414 AA.
AC W9ZDJ2;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=BUB protein kinase {ECO:0000313|EMBL:EXJ92584.1};
GN ORFNames=A1O3_01136 {ECO:0000313|EMBL:EXJ92584.1};
OS Capronia epimyces CBS 606.96.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Capronia.
OX NCBI_TaxID=1182542 {ECO:0000313|EMBL:EXJ92584.1, ECO:0000313|Proteomes:UP000019478};
RN [1] {ECO:0000313|EMBL:EXJ92584.1, ECO:0000313|Proteomes:UP000019478}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 606.96 {ECO:0000313|EMBL:EXJ92584.1,
RC ECO:0000313|Proteomes:UP000019478};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capronia epimyces CBS 606.96.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ92584.1}.
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DR EMBL; AMGY01000001; EXJ92584.1; -; Genomic_DNA.
DR RefSeq; XP_007729474.1; XM_007731284.1.
DR STRING; 1182542.W9ZDJ2; -.
DR GeneID; 19165274; -.
DR eggNOG; KOG1166; Eukaryota.
DR HOGENOM; CLU_002115_1_0_1; -.
DR OrthoDB; 5479089at2759; -.
DR Proteomes; UP000019478; Unassembled WGS sequence.
DR GO; GO:0000776; C:kinetochore; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.430; -; 1.
DR Gene3D; 6.10.20.170; -; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR015661; Bub1/Mad3.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR013212; Mad3/Bub1_I.
DR InterPro; IPR012572; Mad3/Bub1_II.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR14030:SF4; BUB1 KINASE, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR14030; MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1; 1.
DR Pfam; PF08311; Mad3_BUB1_I; 1.
DR Pfam; PF08171; Mad3_BUB1_II; 1.
DR SMART; SM00777; Mad3_BUB1_I; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51489; BUB1_N; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EXJ92584.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019478};
KW Transferase {ECO:0000313|EMBL:EXJ92584.1}.
FT DOMAIN 74..233
FT /note="BUB1 N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51489"
FT DOMAIN 1058..1414
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 244..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 405..671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 724..787
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 842..938
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1083..1106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..267
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..454
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 455..492
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..510
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 584..660
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 759..773
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 842..858
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 859..873
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 894..921
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1087..1106
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1414 AA; 156046 MW; 172E1ADC74F8E231 CRC64;
MAVPAADNDL INFDIIETHK ENIQSLPGGR SAKQLASILA PLPTSKAAGV DADADALPTL
SETKTLNDAI RQEYEIELQS IADSDDPLDI YDRYVRWTLN AYPSAQATPQ SQLLPLLERA
TKAFLTSPHY KNDPRYLKLW LHYIRLFSDS PRETFTFLSR HGIGEGLGLF YEEFAAWLES
AGRWIQADEV YKLGIEREAR PTERLVRKYG QFQQRFEARP QSDNEPSSPA LPTVRPALAA
KIDPFASAPP NDDPQGARQQ SAGRGGSGAP SRTGKPKMAI FSDADSAAPA PTKASANITN
GWDNIGSMRE RKKENTIEAR PWAGEKLKAG GRVGTVPKME IFKDPSQELL QPSRASRQRS
EVVNPRTGRA ERAFVNFEAI YPREGNEEFS FEELRAMSRG WMQKDWRAGK PPARSSASPL
KCTSGNIMAA ASPRPKSKPS RSEEAEDVEN LSHSFRQKLE LTSDIPNPSV HDLSTQSMVG
MPESNLPPQP QNANKREKKL KVREVKQETV TVMTRLESPT GKKLKRKNSA TTEPTMTFHS
KAATNDIYDM FNQPLRRPEM ARDDTQSGDD ADFTEGDVDE GYSTTGDGES TGTGRVSGPG
SDFGDDTSSS LPPDATSTQS QADSVSPWSE FTTSKHVPRL ASVSGSSGKI KGSGSSSKGP
GKSKLKHAHK RVLSDDMTEN MASSSQNPTQ TSGLGGFDTQ AIAAIAGGNF DDMDTKAIAM
LAGDFDDDGD EADTIQNQDP GQDQDLDEQG AGAGVNELPE RDGSRHSEHE NNDNTSLNHN
NNNVTTPVDD VFTEITHKPR FIPLPPEDYE PTPIRPYRDP ALVAHNKLPF MTPIVERTES
SLAPSTVFND PDYFNSKTPS RSAKEEDESP SKLKMEALLM SSPQQPATPS SAAKRKLDEA
DDREEEDTAV TPQRKKSLHH TNENSPVPSP AGAKNTKPLK VEDTVFKTPA VPTQSPARRI
LQPAKIHKGP IVADLQCNPC DDAVRQQILA AVHPPLSSYT GYHDHSDHVY NHYQPLKSYA
EKLGKSKVKA SPRKSQSEKT CSKAVPPILK FQGTARVYAV KRQLGEGAFA PVYLVDSYDP
TETETAIGEE SDNKENVSPR GLRTKSSRQD LEALKTEAPP GTLVWEFHIL RLIRQRLGHA
ARAVQSIVDA HECHLYRDEA YIVLSYSPQG TLLDLVNLAR SENVKAGKLA EGLDETLAMW
FGVELLRTLE DLHRIGILHG DLKGDNCLVR FDSSVDLSGP FDPSGNHGWS AKGLKMIDFG
RGIDVRMFQP SAQFIADWPS SAQDCAEIRE CRPWKWQIDY HGAAGVIHSL LFGKYIETVP
LTAASGGLAL GPRQKKEWKL KENLKRYWEK ELWQEVFSVL LNPGSVSDQE AMPIEGNLKR
VRMKMEKWLV DEGERGGRDL RASLRKMERL VAMK
//
