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Database: UniProt
Entry: W9ZER9_9EURO
LinkDB: W9ZER9_9EURO
Original site: W9ZER9_9EURO 
ID   W9ZER9_9EURO            Unreviewed;       268 AA.
AC   W9ZER9;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   31-JUL-2019, entry version 21.
DE   RecName: Full=Nicotinamide-nucleotide adenylyltransferase {ECO:0000256|RuleBase:RU362021};
DE            EC=2.7.7.1 {ECO:0000256|RuleBase:RU362021};
GN   ORFNames=A1O3_01555 {ECO:0000313|EMBL:EXJ92999.1};
OS   Capronia epimyces CBS 606.96.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Capronia.
OX   NCBI_TaxID=1182542 {ECO:0000313|EMBL:EXJ92999.1, ECO:0000313|Proteomes:UP000019478};
RN   [1] {ECO:0000313|EMBL:EXJ92999.1, ECO:0000313|Proteomes:UP000019478}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 606.96 {ECO:0000313|EMBL:EXJ92999.1,
RC   ECO:0000313|Proteomes:UP000019478};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA   Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA   Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C.,
RA   Murphy C., Pearson M., Poon T.W., Priest M., Roberts A., Saif S.,
RA   Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Capronia epimyces CBS 606.96.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + beta-nicotinamide D-ribonucleotide + H(+) =
CC         diphosphate + NAD(+); Xref=Rhea:RHEA:21360, ChEBI:CHEBI:14649,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:57540; EC=2.7.7.1;
CC         Evidence={ECO:0000256|RuleBase:RU362021};
CC   -!- PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from
CC       nicotinamide D-ribonucleotide: step 1/1.
CC       {ECO:0000256|RuleBase:RU362021}.
CC   -!- SIMILARITY: Belongs to the eukaryotic NMN adenylyltransferase
CC       family. {ECO:0000256|RuleBase:RU362021}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EXJ92999.1}.
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DR   EMBL; AMGY01000001; EXJ92999.1; -; Genomic_DNA.
DR   RefSeq; XP_007729889.1; XM_007731699.1.
DR   STRING; 43228.XP_007729889.1; -.
DR   EnsemblFungi; EXJ92999; EXJ92999; A1O3_01555.
DR   GeneID; 19165689; -.
DR   OrthoDB; 1308027at2759; -.
DR   UniPathway; UPA00253; UER00600.
DR   Proteomes; UP000019478; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000309; F:nicotinamide-nucleotide adenylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.40.50.620; -; 1.
DR   InterPro; IPR004821; Cyt_trans-like.
DR   InterPro; IPR005248; NadD/NMNAT.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   Pfam; PF01467; CTP_transf_like; 1.
DR   TIGRFAMs; TIGR00482; TIGR00482; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU362021};
KW   Complete proteome {ECO:0000313|Proteomes:UP000019478};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   NAD {ECO:0000256|RuleBase:RU362021};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362021};
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU362021,
KW   ECO:0000313|EMBL:EXJ92999.1};
KW   Pyridine nucleotide biosynthesis {ECO:0000256|RuleBase:RU362021};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019478};
KW   Transferase {ECO:0000256|RuleBase:RU362021,
KW   ECO:0000313|EMBL:EXJ92999.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     21     43       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       26    213       CTP_transf_like. {ECO:0000259|Pfam:
FT                                PF01467}.
FT   REGION      242    268       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   268 AA;  30298 MW;  A055B0347C048DF4 CRC64;
     MDDYRFPDSR LKKKMDDPSK TPLLLVACGS FSPITFLHLR MFVMAADYVK HNTNFEIVGG
     YLSPVSDAYK KQGLAPAEHR VAMCQLAIDK ASNWLMVDSW EAEKKEYQPT AKVLDHFDQE
     INVMRKGIDT GDGTRKPVKI SLLAGADLIQ TMSTPGVWSE KDLDHILGRY GVFIIERSGT
     DIDEALASLH NYRENIHVIQ QLIQNDVSST KIRLFLRRGM SVQYLIPAPV VEYIEQNHLY
     GDEHRSSSTP SIVQDNDKGK DKEVEPTA
//
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