ID WRK68_ARATH Reviewed; 277 AA.
AC Q93WV6; Q9LZQ6;
DT 11-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 27-MAR-2024, entry version 127.
DE RecName: Full=WRKY transcription factor 68;
DE AltName: Full=WRKY DNA-binding protein 68;
GN Name=WRKY68; OrderedLocusNames=At3g62340; ORFNames=T12C14.40;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia; TISSUE=Flower;
RA Ulker B., Kushnir S., Somssich I.E.;
RT "Arabidopsis thaliana transcription factor WRKY68.";
RL Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: Transcription factor. Interacts specifically with the W box
CC (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-
CC acting element (By similarity). {ECO:0000250}.
CC -!- INTERACTION:
CC Q93WV6; Q84JU4: IBR5; NbExp=3; IntAct=EBI-25512440, EBI-604555;
CC Q93WV6; O64722: ZHD3; NbExp=3; IntAct=EBI-25512440, EBI-1806244;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the WRKY group II-c family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB82948.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AF421155; AAL13044.1; -; mRNA.
DR EMBL; AL162507; CAB82948.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE80341.1; -; Genomic_DNA.
DR PIR; T48026; T48026.
DR RefSeq; NP_567127.1; NM_116099.3.
DR AlphaFoldDB; Q93WV6; -.
DR SMR; Q93WV6; -.
DR BioGRID; 10721; 2.
DR IntAct; Q93WV6; 2.
DR PaxDb; 3702-AT3G62340-1; -.
DR EnsemblPlants; AT3G62340.1; AT3G62340.1; AT3G62340.
DR GeneID; 825407; -.
DR Gramene; AT3G62340.1; AT3G62340.1; AT3G62340.
DR KEGG; ath:AT3G62340; -.
DR Araport; AT3G62340; -.
DR TAIR; AT3G62340; WRKY68.
DR eggNOG; ENOG502QU0Y; Eukaryota.
DR HOGENOM; CLU_033779_0_0_1; -.
DR InParanoid; Q93WV6; -.
DR OMA; LFDYNNH; -.
DR OrthoDB; 650323at2759; -.
DR PhylomeDB; Q93WV6; -.
DR PRO; PR:Q93WV6; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q93WV6; baseline and differential.
DR Genevisible; Q93WV6; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 2.20.25.80; WRKY domain; 1.
DR InterPro; IPR017396; TF_WRKY_IIc.
DR InterPro; IPR003657; WRKY_dom.
DR InterPro; IPR036576; WRKY_dom_sf.
DR InterPro; IPR044810; WRKY_plant.
DR PANTHER; PTHR31221:SF385; WRKY TRANSCRIPTION FACTOR 68; 1.
DR PANTHER; PTHR31221; WRKY TRANSCRIPTION FACTOR PROTEIN 1-RELATED; 1.
DR Pfam; PF03106; WRKY; 1.
DR PIRSF; PIRSF038130; TF_WRKY_IIc; 1.
DR SMART; SM00774; WRKY; 1.
DR SUPFAM; SSF118290; WRKY DNA-binding domain; 1.
DR PROSITE; PS50811; WRKY; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..277
FT /note="WRKY transcription factor 68"
FT /id="PRO_0000133709"
FT DNA_BIND 112..177
FT /note="WRKY"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00223"
FT REGION 51..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 183..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 52..67
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 277 AA; 31678 MW; 24BF78B413AF101C CRC64;
MENVGVGMPF YDLGQTRVYP LLSDFHDLSA ERYPVGFMDL LGVHRHTPTH TPLMHFPTTP
NSSSSEAVNG DDEEEEDGEE QQHKTKKRFK FTKMSRKQTK KKVPKVSFIT RSEVLHLDDG
YKWRKYGQKP VKDSPFPRNY YRCTTTWCDV KKRVERSFSD PSSVITTYEG QHTHPRPLLI
MPKEGSSPSN GSASRAHIGL PTLPPQLLDY NNQQQQAPSS FGTEYINRQE KGINHDDDDD
HVVKKSRTRD LLDGAGLVKD HGLLQDVVPS HIIKEEY
//
