ID X0C3Z1_FUSOX Unreviewed; 601 AA.
AC X0C3Z1;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Arylsulfatase {ECO:0000256|PIRNR:PIRNR000972};
DE Short=AS {ECO:0000256|PIRNR:PIRNR000972};
DE EC=3.1.6.1 {ECO:0000256|PIRNR:PIRNR000972};
DE AltName: Full=Aryl-sulfate sulphohydrolase {ECO:0000256|PIRNR:PIRNR000972};
GN ORFNames=FOQG_10588 {ECO:0000313|EMBL:EXK85514.1};
OS Fusarium oxysporum f. sp. raphani 54005.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1089458 {ECO:0000313|EMBL:EXK85514.1, ECO:0000313|Proteomes:UP000030663};
RN [1] {ECO:0000313|EMBL:EXK85514.1, ECO:0000313|Proteomes:UP000030663}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=54005 {ECO:0000313|EMBL:EXK85514.1,
RC ECO:0000313|Proteomes:UP000030663};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusarium oxysporum PHW815.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=an aryl sulfate + H2O = a phenol + H(+) + sulfate;
CC Xref=Rhea:RHEA:17261, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16189, ChEBI:CHEBI:33853, ChEBI:CHEBI:140317; EC=3.1.6.1;
CC Evidence={ECO:0000256|PIRNR:PIRNR000972};
CC -!- PTM: The conversion to 3-oxoalanine (also known as C-formylglycine,
CC FGly), of a serine or cysteine residue in prokaryotes and of a cysteine
CC residue in eukaryotes, is critical for catalytic activity.
CC {ECO:0000256|PIRSR:PIRSR000972-50}.
CC -!- SIMILARITY: Belongs to the sulfatase family.
CC {ECO:0000256|ARBA:ARBA00008779, ECO:0000256|PIRNR:PIRNR000972}.
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DR EMBL; JH658389; EXK85514.1; -; Genomic_DNA.
DR AlphaFoldDB; X0C3Z1; -.
DR eggNOG; KOG3731; Eukaryota.
DR Proteomes; UP000030663; Unassembled WGS sequence.
DR GO; GO:0004065; F:arylsulfatase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0018958; P:phenol-containing compound metabolic process; IEA:InterPro.
DR CDD; cd16147; G6S; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR012083; Arylsulfatase.
DR InterPro; IPR024607; Sulfatase_CS.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR43108; N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43108:SF8; SD21168P; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR PIRSF; PIRSF000972; Arylsulf_plant; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS00523; SULFATASE_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PIRNR:PIRNR000972};
KW Reference proteome {ECO:0000313|Proteomes:UP000030663};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..601
FT /note="Arylsulfatase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004936745"
FT DOMAIN 54..404
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT MOD_RES 98
FT /note="3-oxoalanine (Cys)"
FT /evidence="ECO:0000256|PIRSR:PIRSR000972-50"
SQ SEQUENCE 601 AA; 67166 MW; 2C1DECC2F8A14777 CRC64;
MRPPAWIQPV LLASCLLAES TNASFNYEPE DQAVLSPNND AAQSKPKTNN GGKKNIVFIL
TDDQDAVLNS VSYMPKLKEH IIDKGTSFVN HFTTTAICCP SRVALWTGKQ PHNTNVTDVN
PPYGGFPKFV SQGLNENYLP VWLKEAGYNT YYTGKLFNAH TINNYNSPYP AGWTGTNFLL
DPGTYDYLNP IYQHNQEPPV QHKGVHTSDL ISKYAHELLK EAIDAENPFF VAIAPVAPHS
NVNLRRQPGN PSAPLMTIPI PLERHSHLFE GVKVPRTENF NPDSPSGVSW IHKLAQLNDS
SVSYLDDFYR ARLQALQGVD EIVEQVTKQL EDAGILDETY IIYSSDNGYH LGQHRLPPGK
ECGFDEDIRV PLFIRGPGVS SGSIENAVTT HIDLAPTILR LAGADLRSDF DGTPIPVLPT
QENKRHEHVA VEYWGGAIAE GEIGGFDGKG QIFAQNNTYK GVRIVHEDYN LYYSAWCNNE
HELYDLKTDP GQLKSLFPHD DTTADSALLG TTARQVLNRL DALMLVLKSC KGNTCIEPWK
ILHPEGGVTS LKDALQAKFN AFYKEQVKVR FDRCEYGYLI DAEGPQVGYE YREGLEWHHW
T
//
