ID X0C4R0_FUSOX Unreviewed; 712 AA.
AC X0C4R0;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Purple acid phosphatase {ECO:0000256|RuleBase:RU361203};
DE EC=3.1.3.2 {ECO:0000256|RuleBase:RU361203};
GN ORFNames=FOQG_17568 {ECO:0000313|EMBL:EXK77732.1};
OS Fusarium oxysporum f. sp. raphani 54005.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1089458 {ECO:0000313|EMBL:EXK77732.1, ECO:0000313|Proteomes:UP000030663};
RN [1] {ECO:0000313|EMBL:EXK77732.1, ECO:0000313|Proteomes:UP000030663}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=54005 {ECO:0000313|EMBL:EXK77732.1,
RC ECO:0000313|Proteomes:UP000030663};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusarium oxysporum PHW815.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC Evidence={ECO:0000256|RuleBase:RU361203};
CC -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. Purple
CC acid phosphatase family. {ECO:0000256|RuleBase:RU361203}.
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DR EMBL; KI979377; EXK77732.1; -; Genomic_DNA.
DR AlphaFoldDB; X0C4R0; -.
DR eggNOG; KOG1378; Eukaryota.
DR HOGENOM; CLU_013387_2_2_1; -.
DR Proteomes; UP000030663; Unassembled WGS sequence.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd00839; MPP_PAPs; 1.
DR Gene3D; 3.60.21.10; -; 2.
DR Gene3D; 2.60.40.380; Purple acid phosphatase-like, N-terminal; 1.
DR InterPro; IPR014390; Acid_Pase_Asper.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041792; MPP_PAP.
DR InterPro; IPR039331; PPA-like.
DR InterPro; IPR008963; Purple_acid_Pase-like_N.
DR InterPro; IPR015914; Purple_acid_Pase_N.
DR InterPro; IPR025733; Purple_acid_PPase_C_dom.
DR PANTHER; PTHR22953; ACID PHOSPHATASE RELATED; 1.
DR PANTHER; PTHR22953:SF159; PURPLE ACID PHOSPHATASE; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF14008; Metallophos_C; 1.
DR Pfam; PF16656; Pur_ac_phosph_N; 1.
DR PIRSF; PIRSF000900; Acid_Ptase_Asper; 2.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF49363; Purple acid phosphatase, N-terminal domain; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361203};
KW Reference proteome {ECO:0000313|Proteomes:UP000030663};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU361203}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT CHAIN 18..712
FT /note="Purple acid phosphatase"
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT /id="PRO_5005152133"
FT DOMAIN 84..176
FT /note="Purple acid phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16656"
FT DOMAIN 478..564
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 593..657
FT /note="Iron/zinc purple acid phosphatase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14008"
SQ SEQUENCE 712 AA; 79099 MW; F858F4A899156887 CRC64;
MKSSYFFAGI FAALTQAAPT VDEKYPYNGP KIPIGDWVDP TIKGNGKGFH RLVEHPAVQP
ASDNATNNIN VISLSYIPAK SGGDTVGINI HYQTPFGLGL APSVYWGTSP SSLNNVATGL
TATYDRTPPC SLVAVTQCSQ FFHNVQIEQL QPGTTYFYQI PAANGTTQST VLSFTTAQAT
GNPSQFSIAI NNDMGYTNAG GTYKYMNQAM DDEDGLAFVW HGGDLSYADD WYSGIIQCNA
SVWPVCYNGS FSSLPNNDTN PDYFDTPLPA HEIPNQGSPR GGDVGVLYES NWDLWQQWMN
NITMKIPYIV LPGNHEATCA DHDNTPYVLS SYLNENKTNT TMSGDNPNAT LTYYSCPPSQ
RNFTAFQNRF FMAGDKSGGV GNFWHSFDYG LVHFVSIDTE TDYAHSPDKT FREDIEKAKE
EEDCKGKDKD KAKCKPEKDE SDTYECKKIN LCDDYETDAL EEETYLLSGK AHPLRNETHI
TDAGPFGYID GSVKDNKAYE QYQWLKEDLH KVDRCKTPWV IVMGHRPMYS SHGGNYHLHL
REAFEKLLLK HKVDLYIAGH VHWYERLKPI RNCDVDTRLV KSPNTYEVNP GYSMVHLING
AAGNIESHST INMSQPLPNI TAHRNLTSFG FSKLTVYNAT TLSWQFIQGH DGLVGDELTV
LKDPSLTCEG YNYSSASGSS GSSCSSECSG SGLLAWVYCN LYCSSFWEPL KL
//
