ID   X0D0V0_FUSOX            Unreviewed;       563 AA.
AC   X0D0V0;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=PNPLA domain-containing protein {ECO:0000259|PROSITE:PS51635};
GN   ORFNames=FOQG_08615 {ECO:0000313|EMBL:EXK88307.1};
OS   Fusarium oxysporum f. sp. raphani 54005.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium oxysporum species complex.
OX   NCBI_TaxID=1089458 {ECO:0000313|EMBL:EXK88307.1, ECO:0000313|Proteomes:UP000030663};
RN   [1] {ECO:0000313|EMBL:EXK88307.1, ECO:0000313|Proteomes:UP000030663}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=54005 {ECO:0000313|EMBL:EXK88307.1,
RC   ECO:0000313|Proteomes:UP000030663};
RG   The Broad Institute Genome Sequencing Platform;
RA   Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA   Freedman E., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA   Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA   Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Fusarium oxysporum PHW815.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable lipid hydrolase. {ECO:0000256|ARBA:ARBA00002682}.
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DR   EMBL; KI979323; EXK88307.1; -; Genomic_DNA.
DR   AlphaFoldDB; X0D0V0; -.
DR   eggNOG; KOG2214; Eukaryota.
DR   HOGENOM; CLU_009031_5_0_1; -.
DR   Proteomes; UP000030663; Unassembled WGS sequence.
DR   GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:UniProt.
DR   CDD; cd07229; Pat_TGL3_like; 1.
DR   Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR002641; PNPLA_dom.
DR   InterPro; IPR021771; Triacylglycerol_lipase_N.
DR   PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR   PANTHER; PTHR14226:SF44; TRIACYLGLYCEROL LIPASE 3; 1.
DR   Pfam; PF11815; DUF3336; 1.
DR   Pfam; PF01734; Patatin; 1.
DR   SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR   PROSITE; PS51635; PNPLA; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030663}.
FT   DOMAIN          165..365
FT                   /note="PNPLA"
FT                   /evidence="ECO:0000259|PROSITE:PS51635"
SQ   SEQUENCE   563 AA;  62946 MW;  56E023A188B9996E CRC64;
     MSLQKLRSWY TRKSPVELWL DLLRTAEAFE DWEEAALHLD NLLGLDLWRN NPASKYYDWR
     LIAERLDSLA TAREDGNFQQ LVNLLRSGLV RNLGNITSPK LYNRSFAGTK YLIEEYITQI
     AEAVEDIRAL PTTPSAIHGT GPSLTTQMKL DCIHDTRQAF GRSTLVLQGG AIFGMCHLGV
     VKALFLRGLL PRIITGTATG ALIAALVAIH TEDELPAVLS GDGIDLSAFA SKNGHENGET
     STAQTFRSRW ETLLRRIRRF SKEGYFLDVT VLEECVRANV GDLTFEEAYN RSKRVLNITV
     ATEGQGGVPT LLNYLTAPNV LIWTAAVASN ASSPSLYGHR KTTMLCKDAH GSIVPWAPAN
     TIDFRHWTHT SYSDRDSPLR RIAELFNVNH FIVSQARPYL IPFIQSDMHG PSLVESRSKT
     TQISAFLVRM VGLEIRHRLS QLDTLNLLPT GIRRFLVDEQ VPAASMVLVP EVTAGDFVRL
     LETPTRETLN YWVLRGERSV WPAVAALRIR CAVENELDRS YQVVRKFKAP GLRRKGSMAA
     TLEAERRERN GQFGSAVTDI SAT
//