ID X0DCA5_FUSOX Unreviewed; 665 AA.
AC X0DCA5;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=PLD phosphodiesterase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=FOQG_06075 {ECO:0000313|EMBL:EXK92162.1};
OS Fusarium oxysporum f. sp. raphani 54005.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1089458 {ECO:0000313|EMBL:EXK92162.1, ECO:0000313|Proteomes:UP000030663};
RN [1] {ECO:0000313|EMBL:EXK92162.1, ECO:0000313|Proteomes:UP000030663}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=54005 {ECO:0000313|EMBL:EXK92162.1,
RC ECO:0000313|Proteomes:UP000030663};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusarium oxysporum PHW815.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JH658371; EXK92162.1; -; Genomic_DNA.
DR AlphaFoldDB; X0DCA5; -.
DR Proteomes; UP000030663; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd09122; PLDc_Tdp1_1; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR010347; Tdp1.
DR InterPro; IPR003903; UIM_dom.
DR PANTHER; PTHR12415; TYROSYL-DNA PHOSPHODIESTERASE 1; 1.
DR PANTHER; PTHR12415:SF4; TYROSYL-DNA PHOSPHODIESTERASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF06087; Tyr-DNA_phospho; 1.
DR Pfam; PF02809; UIM; 1.
DR SMART; SM00726; UIM; 1.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50330; UIM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030663}.
FT REGION 26..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 467..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 548..650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..96
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..493
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..575
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 589..603
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 220
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR610347-1"
FT ACT_SITE 458
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR610347-1"
FT BINDING 222
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR610347-2"
FT BINDING 460
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR610347-2"
FT SITE 513
FT /note="Interaction with DNA"
FT /evidence="ECO:0000256|PIRSR:PIRSR610347-3"
SQ SEQUENCE 665 AA; 73330 MW; 16C87F62B096A238 CRC64;
MAGSREDPVE LGSDMDEDEA LRYAIALSLQ EQEEQGDQSS QIPSASTSTS HRKGTGSGGA
SLGLLSLDRK KMEEERLQRL AKRRRSPEDE RSVYEVPPAK RMTPSEPSRT VTATATAHVL
PSFVPYPKGA IKRTWAKGYP RTSDDIKIEE VFQKDKLELA LLSSYQWDDE WLMSKIDPRK
TKLLLLAFAD SEAQKSEMRS NAPPGIKFVF PAMNGPGAMH SKLQLLKYPD YLRVVVPTAN
LVPYDWGETG VMENMVFLID LPRLKDPATY RQTAFSTELG RFLSATGVGE GMVSSLANYD
FSQTKHLGFV YTIPGGHQGD SLKRIGYSGL GTTVAALGLA TDEPIEVDFV CASLGSLNYD
LVGAIYNACQ GDDGMVEYKS RIGRTGAASK NKASNPWQEK LKDRFRIYFP TEETVGRSRG
GRNAAGTICV QPKWWRSPTF PTELVRDCVN TRDGLLMHSK MIMVSQMQAG SQLQTRPQTR
PEPRHHDSGP AAAEPKTEEM SLGWVYIGSA NLSESAWGRI VKDRATGQPK MSCRNWESGV
VVRISNPKNS STVSASFSTS ASAGASSSTK VKAAEGQARS SVRAGKISGE PDKGCDTSQH
NHHHYQMQKQ NQKQKQEEGL TDTDAHTDSD MMSGTVFEGT VPIPMRRPGR RYREGEEPWF
YSVQG
//
