GenomeNet

Database: UniProt
Entry: X1WBT8_DANRE
LinkDB: X1WBT8_DANRE
Original site: X1WBT8_DANRE 
ID   X1WBT8_DANRE            Unreviewed;       132 AA.
AC   X1WBT8;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   31-JUL-2019, entry version 31.
DE   SubName: Full=Epsin 2 {ECO:0000313|Ensembl:ENSDARP00000127680};
DE   Flags: Fragment;
GN   Name=epn2 {ECO:0000313|Ensembl:ENSDARP00000127680,
GN   ECO:0000313|ZFIN:ZDB-GENE-071212-1};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000127680, ECO:0000313|Proteomes:UP000000437};
RN   [1] {ECO:0000313|Ensembl:ENSDARP00000127680, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000127680,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
RN   [2] {ECO:0000313|Ensembl:ENSDARP00000127680}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000127680};
RG   Ensembl;
RL   Submitted (MAR-2014) to UniProtKB.
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DR   EMBL; BX322795; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSDART00000153866; ENSDARP00000127680; ENSDARG00000008377.
DR   ZFIN; ZDB-GENE-071212-1; epn2.
DR   eggNOG; KOG2056; Eukaryota.
DR   eggNOG; ENOG410XSM0; LUCA.
DR   GeneTree; ENSGT00940000157239; -.
DR   Proteomes; UP000000437; Chromosome 3.
DR   Bgee; ENSDARG00000008377; Expressed in 27 organ(s), highest expression level in gastrula.
DR   ExpressionAtlas; X1WBT8; baseline and differential.
DR   GO; GO:0030128; C:clathrin coat of endocytic vesicle; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR   Gene3D; 1.25.40.90; -; 1.
DR   InterPro; IPR013809; ENTH.
DR   InterPro; IPR008942; ENTH_VHS.
DR   InterPro; IPR027319; Epsin-2_metazoa.
DR   PANTHER; PTHR12276:SF50; PTHR12276:SF50; 1.
DR   Pfam; PF01417; ENTH; 1.
DR   SUPFAM; SSF48464; SSF48464; 1.
DR   PROSITE; PS50942; ENTH; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:X1WBT8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT   DOMAIN        1     55       ENTH. {ECO:0000259|PROSITE:PS50942}.
FT   REGION       72    106       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS     72     99       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSDARP00000127680}.
SQ   SEQUENCE   132 AA;  14679 MW;  E6A901BDAE744117 CRC64;
     XRVALQCKEN IFAIQTLKDF QYIDRDGKDQ GINVREKSKQ LVVLLKDDDR LKGERSQALK
     TKERMAQVAT SVGSNNQIGF GRGSSQPNLS TSYSEEYGKS EGSPASYHGY QETAGVLLPC
     RRHILSCASL QQ
//
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