ID X2HD47_9NEIS Unreviewed; 105 AA.
AC X2HD47;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Guanidinium exporter {ECO:0000256|ARBA:ARBA00039168};
GN ORFNames=SALWKB2_1610 {ECO:0000313|EMBL:AHN28992.1};
OS Snodgrassella alvi wkB2.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Snodgrassella.
OX NCBI_TaxID=1196094 {ECO:0000313|EMBL:AHN28992.1, ECO:0000313|Proteomes:UP000019668};
RN [1] {ECO:0000313|EMBL:AHN28992.1, ECO:0000313|Proteomes:UP000019668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WkB2 {ECO:0000313|EMBL:AHN28992.1};
RX PubMed=25053814;
RA Kwong W.K., Engel P., Koch H., Moran N.A.;
RT "Genomics and host specialization of honey bee and bumble bee gut
RT symbionts.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:11509-11514(2014).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU003942};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU003942}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
CC Gdx/SugE subfamily. {ECO:0000256|ARBA:ARBA00038151}.
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DR EMBL; CP007446; AHN28992.1; -; Genomic_DNA.
DR RefSeq; WP_025331179.1; NZ_CP091515.1.
DR AlphaFoldDB; X2HD47; -.
DR STRING; 1196094.SALWKB2_1610; -.
DR GeneID; 32538239; -.
DR KEGG; salv:SALWKB2_1610; -.
DR PATRIC; fig|1196094.4.peg.1611; -.
DR HOGENOM; CLU_133067_1_2_4; -.
DR OrthoDB; 9808638at2; -.
DR Proteomes; UP000019668; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR Gene3D; 1.10.3730.20; -; 1.
DR InterPro; IPR000390; Small_drug/metabolite_transptr.
DR InterPro; IPR045324; Small_multidrug_res.
DR PANTHER; PTHR30561:SF0; GUANIDINIUM EXPORTER; 1.
DR PANTHER; PTHR30561; SMR FAMILY PROTON-DEPENDENT DRUG EFFLUX TRANSPORTER SUGE; 1.
DR Pfam; PF00893; Multi_Drug_Res; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|RuleBase:RU003942, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 105 AA; 10924 MW; 218F7ABD73134A79 CRC64;
MAWVSLLLAG ILEIVWAIGL KYSQNFTKFT PSIITLAALV GSFLLLAQSM RSLPVGTAYA
VWTGIGAVGA TIVGIIAFKE PAGAMRLISL TLIIAGIIGL KLGAH
//
