ID X5D7B0_9BACT Unreviewed; 590 AA.
AC X5D7B0;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Precorrin-4 C11-methyltransferase {ECO:0000313|EMBL:SET89282.1};
GN ORFNames=SAMN05444285_12748 {ECO:0000313|EMBL:SET89282.1};
OS Draconibacterium orientale.
OC Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Prolixibacteraceae;
OC Draconibacterium.
OX NCBI_TaxID=1168034 {ECO:0000313|EMBL:SET89282.1, ECO:0000313|Proteomes:UP000181981};
RN [1] {ECO:0000313|EMBL:SET89282.1, ECO:0000313|Proteomes:UP000181981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25947 {ECO:0000313|EMBL:SET89282.1,
RC ECO:0000313|Proteomes:UP000181981};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOHT01000027; SET89282.1; -; Genomic_DNA.
DR RefSeq; WP_038554194.1; NZ_FOHT01000027.1.
DR AlphaFoldDB; X5D7B0; -.
DR STRING; 1168034.FH5T_00435; -.
DR GeneID; 78100747; -.
DR eggNOG; COG2073; Bacteria.
DR eggNOG; COG2875; Bacteria.
DR HOGENOM; CLU_028397_1_1_10; -.
DR OrthoDB; 9815856at2; -.
DR Proteomes; UP000181981; Unassembled WGS sequence.
DR GO; GO:0046026; F:precorrin-4 C11-methyltransferase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11641; Precorrin-4_C11-MT; 1.
DR Gene3D; 3.40.50.11220; -; 1.
DR Gene3D; 3.30.420.180; CobE/GbiG C-terminal domain; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR021745; CbiG_mid.
DR InterPro; IPR021744; CbiG_N.
DR InterPro; IPR006362; Cbl_synth_CobM/CibF.
DR InterPro; IPR002750; CobE/GbiG_C.
DR InterPro; IPR036518; CobE/GbiG_C_sf.
DR InterPro; IPR038029; GbiG_N_sf.
DR NCBIfam; TIGR01465; cobM_cbiF; 1.
DR PANTHER; PTHR37477; COBALT-PRECORRIN-5A HYDROLASE; 1.
DR PANTHER; PTHR37477:SF1; COBALT-PRECORRIN-5A HYDROLASE; 1.
DR Pfam; PF01890; CbiG_C; 1.
DR Pfam; PF11761; CbiG_mid; 1.
DR Pfam; PF11760; CbiG_N; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF159672; CbiG N-terminal domain-like; 1.
DR SUPFAM; SSF159664; CobE/GbiG C-terminal domain-like; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:SET89282.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SET89282.1}.
FT DOMAIN 35..113
FT /note="Cobalamin synthesis G N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11760"
FT DOMAIN 118..208
FT /note="Cobalamin biosynthesis central region"
FT /evidence="ECO:0000259|Pfam:PF11761"
FT DOMAIN 211..331
FT /note="CobE/GbiG C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01890"
FT DOMAIN 344..547
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 590 AA; 65238 MW; AF2D27C974566012 CRC64;
MISIITHSET GKALAEKILR KEPDAKMIQK PVDYNKLWQT GHALVFIGAL GICVREIAPF
LKNKKTDPAV INIDANGQFV QPVVSGHIGG ANELAKKLAN LLGATPVLTT VSDTSELWAL
DVLPRQFNWK MECSGNHTSL TGHFVNRKKT ALLLETRDKG TLFLESGCPE FVDVFYSRKE
LNTENYNLIL AITPFLHDFG DKAIFYRPPM VCLGLGCQRG LPYEEFQQTL EKSLKEQGIS
SLSVASLATA ELKKDEDAFL QLSREWGVLL HSISSEVLAK YNVPNPSEKV EVVTGSAGVA
EAAAMHLAEN GLLIQKTKLQ AGNKFFTYAV AIDAQKERKG FVEFVGAGPG DPELVSVKGK
RLLQTADYIL YAGSLVPREL TEYAKSGCVV ESSAGMDLYT QLESMKQYYD KGLSVVRLHT
GDPCIYGAIQ EQMAIMDKWG WHYHITPGIS SFQAAAAALR SQFTIPEEVQ TIILTRGEGR
TPMPEKEQLN KLAQSQSTMC IYLSAAIAQK VQADLLAHYP PETPVAVCYK LTWQDEKIYR
CTLETLAQTV KENKLTMTTL IVVGKAIDNR SGESKLYDRK FAHAFRKGCE
//
