ID X5DBI8_9BACT Unreviewed; 718 AA.
AC X5DBI8;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Tetracycline resistance protein TetQ {ECO:0000256|ARBA:ARBA00013902};
GN ORFNames=SAMN05444285_10467 {ECO:0000313|EMBL:SES97117.1};
OS Draconibacterium orientale.
OC Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Prolixibacteraceae;
OC Draconibacterium.
OX NCBI_TaxID=1168034 {ECO:0000313|EMBL:SES97117.1, ECO:0000313|Proteomes:UP000181981};
RN [1] {ECO:0000313|EMBL:SES97117.1, ECO:0000313|Proteomes:UP000181981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25947 {ECO:0000313|EMBL:SES97117.1,
RC ECO:0000313|Proteomes:UP000181981};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Abolishes the inhibitory effect of tetracyclin on protein
CC synthesis by a non-covalent modification of the ribosomes.
CC {ECO:0000256|ARBA:ARBA00003987}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FOHT01000004; SES97117.1; -; Genomic_DNA.
DR RefSeq; WP_038558937.1; NZ_FOHT01000004.1.
DR AlphaFoldDB; X5DBI8; -.
DR STRING; 1168034.FH5T_12700; -.
DR GeneID; 78098657; -.
DR eggNOG; COG0480; Bacteria.
DR HOGENOM; CLU_002794_4_2_10; -.
DR OrthoDB; 9801591at2; -.
DR Proteomes; UP000181981; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd04170; EF-G_bact; 1.
DR CDD; cd01434; EFG_mtEFG1_IV; 1.
DR CDD; cd03713; EFG_mtEFG_C; 1.
DR CDD; cd04088; EFG_mtEFG_II; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR047872; EFG_IV.
DR InterPro; IPR035649; EFG_V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43261:SF7; ELONGATION FACTOR G-LIKE PROTEIN; 1.
DR PANTHER; PTHR43261; TRANSLATION ELONGATION FACTOR G-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 2.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:SES97117.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000313|EMBL:SES97117.1}.
SQ SEQUENCE 718 AA; 79370 MW; BA4F9773E2DF79C3 CRC64;
MKVYKTDEVR NIALIGNAGS GKTTLAEAML FEGGIINRKG DVGSKNTVSD YNPIEQDYGN
SVFSTLMHTE YNGKKINIMD TPGMDDLCGG VVSSLSVTAL GLLTVNASNG IEAGTEAAAR
HADNAHTPLV VVFNQLDHEN SNFDSTLDQC KTAFGNKTTV VQYPVDPGTG FSAIIDVLKM
KMYTYKDDSG KPEISDIPES ELEKAEELHN ELVEKAAENE EALMELYFDK GTLTEDEMRK
GIKLGMLDLT LFPVFCTCAR KSIGVGRLME FITNIAPTPK EKKMGKIVAG KEVTMDASQP
PSLFVFKTAV EPHVGEITYF KVMSGVVKEG LDLINSKTGN KERLSQVFVP DGKSREKVDE
LHAGDLGCTV KLKETRFNQT LAAKEIGTAF APIEFPTPRH TVAAKAVNDS DDEKVGEILS
KIKYEDPTYV IEYSKELKQQ LIHAQGEYHL NVLKWYFDHV HKVDVEYLKP KIPYRETITK
PAQADYRHKK QSGGAGQFGE VHMIIEPYEE GAAPKTMFKF GDKEQKISVR AVEEHKLDWG
GKLVFVNSIV GGSIDARFLP AILKGIMEKI EEGPLTGSYA RDIIVYVYDG KMHPVDSNEI
SFKLAGRNAF SMAFKNASPK ILEPILNLEV WVPSDRMGDA MSDLQGRRAM IMGMGSEKGL
EKITAKVPQK EMFKYTTSLS SITGGRGVFS ISFDGYEKVP ADVQEELLKA YEAEQEEE
//
