ID X5H3I6_9RICK Unreviewed; 287 AA.
AC X5H3I6;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Protein HflC {ECO:0000256|PIRNR:PIRNR005651};
GN Name=hflC {ECO:0000313|EMBL:AHX11116.1};
GN ORFNames=NHE_0149 {ECO:0000313|EMBL:AHX11116.1};
OS Neorickettsia helminthoeca str. Oregon.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC Anaplasmataceae; Neorickettsia.
OX NCBI_TaxID=1286528 {ECO:0000313|EMBL:AHX11116.1, ECO:0000313|Proteomes:UP000023755};
RN [1] {ECO:0000313|EMBL:AHX11116.1, ECO:0000313|Proteomes:UP000023755}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Oregon {ECO:0000313|EMBL:AHX11116.1,
RC ECO:0000313|Proteomes:UP000023755};
RA Lin M., Daugherty S.C., Nagaraj S., Cheng Z., Xiong Q., Lin F.-Y.,
RA Sengamalay N., Ott S., Godinez A., Tallon L.J., Sadzewicz L., Fraser C.M.,
RA Dunning Hotopp J.C., Rikihisa Y.;
RT "Sequencing and Comparison of Genomes and Transcriptome Profiles of Human
RT Ehrlichiosis Agents.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: HflC and HflK could regulate a protease.
CC {ECO:0000256|PIRNR:PIRNR005651}.
CC -!- SIMILARITY: Belongs to the band 7/mec-2 family. HflC subfamily.
CC {ECO:0000256|ARBA:ARBA00007862, ECO:0000256|PIRNR:PIRNR005651}.
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DR EMBL; CP007481; AHX11116.1; -; Genomic_DNA.
DR RefSeq; WP_038558864.1; NZ_CP007481.1.
DR AlphaFoldDB; X5H3I6; -.
DR STRING; 1286528.NHE_0149; -.
DR KEGG; nhm:NHE_0149; -.
DR HOGENOM; CLU_059167_3_0_5; -.
DR OrthoDB; 9812991at2; -.
DR Proteomes; UP000023755; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd03405; SPFH_HflC; 1.
DR Gene3D; 3.30.479.30; Band 7 domain; 1.
DR InterPro; IPR001107; Band_7.
DR InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR InterPro; IPR010200; HflC.
DR InterPro; IPR001972; Stomatin_HflK_fam.
DR PANTHER; PTHR42911; MODULATOR OF FTSH PROTEASE HFLC; 1.
DR PANTHER; PTHR42911:SF1; MODULATOR OF FTSH PROTEASE HFLC; 1.
DR Pfam; PF01145; Band_7; 1.
DR PIRSF; PIRSF005651; HflC; 1.
DR PRINTS; PR00721; STOMATIN.
DR SMART; SM00244; PHB; 1.
DR SUPFAM; SSF117892; Band 7/SPFH domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000023755};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 18..181
FT /note="Band 7"
FT /evidence="ECO:0000259|SMART:SM00244"
SQ SEQUENCE 287 AA; 32546 MW; 2BCDA35BE3475ADC CRC64;
MKRTLVVLSI VVVVLLGLSV FVVPEGRQAI VLQFGEVVTS EPLKPGLHFK IPFINNVVRI
DTRILDLSSG SIEVIAADQK RLIVSYYAKY RITDPVQFYR SAKSITNLES RLSPVIESNM
REQVGLVPLI GILTEERGKV MSNIKLQADK VASDFGVEVV DVRIKRADLP GENSEAIFKR
MQTEREKEAR EIRAQGYQEA QRIISTADKE KKLIITNAYS KAQSIKGEGD AEAAKIYSIA
YMVDQEFYKF YRSLIAYERV FEKNNTRFII NSGDRFLSIL KDSNEKK
//
